renal cell carcinoma Flashcards

1
Q

what is a renal cell carcinoma?

A
  • adenocarcinoma of the renal cortex

- most common type of kidney tumour

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2
Q

RCC risk factors

A
  • smoking
  • renal failure and dialysis
  • obesity
  • hypertension
  • low socio economic status
  • asbestos, cadmium exposure, phenacetin
  • genetic (VHL accounts for most sporadic renal cancers and 50% of VHL syndrome will develop RCC)
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3
Q

where do RCC arise from

A

proximal convoluted tubule

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4
Q

True/False

Some RCCs contain cysts

A

True

10-25% contain cysts or are predominantly cystic

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5
Q

how is the difference between cystic kidney disease and cancer predicted?

A

using the Bosniak score

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6
Q

types of RCC?

A
  • Conventional clear cell carcinoma (80%)
  • Papillary (10-15%)
  • Chromophone (5%)
  • Collecting duct
  • Medullary cell
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