Renal Flashcards
Where are the kidneys located at in relation to the peritoneum and the vertebra
retroperitoneum - behind the peritoneum containing the abdominal organs
Lateral to the thoracic vertebrae
At which vertebral levels are the kidneys located at
Right - L1-L3
Left - T12 -L2
Why is the right kidney at a more inferior vertebral level than the left
Due to the size of the liver
At which quadrants are the kidneys located at
Flank (lumbar region) or Upper quadrant regions
Are there any ribs protecting the kidneys
Yes, ribs 11 and 12 are posterior to the kidneys (right behind, no other organs in between) and offer some protection
Why are ribs 11 and 12 called the floating ribs
Because they do not attach to the sternum
What may occur if ribs 11 and 12 fracture
the sharp displaced ends can lacerate the kidney
What structure is lateral to the kidneys
3 layers of anterolateral abdominal wall muscles
What are the 3 layers of anterolateral abdominal wall muscles
external oblique
internal oblique
transversus abdominis
What structure is medial to the kidneys
Renal hilum
What structures make up the renal hilum
Renal artery
Renal vein
Ureter
What structures are anterior to the kidneys- from deep to superficial
Renal capsule
Perinephric fat
Renal deep fascia
Paranephric fat
Visceral peritoneum
What structures lie posterior to the kidneys
Quadratus lumberus
Psoas major (posteromedially)
Ribs 11 and 12
Name A-G
A- visceral peritoneum
B- paranephric fat
C- renal fascia
D- perinephric fat
E- renal capsule
F- quadratus lumborus (left)
G- psoas major (left)
Right kidney lies posteriorly to which organs
Liver
Hepatorenal recess
2nd part of the duodenum
Ascending colon
Right colic flexure
What is the second part of duodenum
descending part
Left kidney lies posteriorly to which organs
Stomach
Tail of the pancreas
Hilum of the spleen
Splenic vessels
Name A and B
A- hepatorenal recess
B- subphrenic space
Name A-E
A- subphrenic space
B- hepatorenal recess
C- Inferior vena cava
D- abdominal aorta
E- duodenum (descending part)
What gland lies on top of the kidneys
adrenal gland
Name A-D
A- spleen
B- splenic artery
C- splenic vein
D- adrenal gland
Describe balloting of the kidneys
palpate posteriorly within just inferior to 12th rib (costovertebral angle) AND palpate anteriorly within the flank region
What is a renal papilla
The apex of renal pyramids
Describe the flow of urine to the bladder
- Urine formed by the renal pyramids
- Minor calyx collects urine from the pyramid
- Several minor calyx join together to form major calyx
- Urine pass through major calyx to reach the renal pelvis
- Urine drains into the ureter from the renal pelvis then to the bladder
Name A-I
A- renal cortex
B- renal papilla
C- minor calyx
D- major calyx
E- renal pelvis
F- ureter
G- renal column
H- renal pyramid
I- renal sinus
What is renal sinus
Compartment inside the kidney that uses fat to cushion the calyx / renal pelvis/ vessels etc
What are the variations of kidneys
Bifid renal pelvis (most common)
Bifid ureter
Unilateral duplicated ureter
Retrocaval ureter
Horseshoe kidney
Ectopic pelvis kidney
Name A-E
A- bifid renal pelvis
B- bifid ureter and unilateral duplicated ureter
C- retrocaval ureter
D- horseshoe kidney
E- ectopic pelvis kidney
What is retrocaval ureter
When the ureter is BEHIND the IVC instead of anterior
What are the 3 constriction sites of the ureter
Pelviureteric junction
Ureter crossing the common iliac artery
Vesicoureteric junction
What gives the renal pyramids a striped appearance
Regularly arranged nephrons running axially towards the apex of each pyramid
What does the renal corpuscle contain
glomerulus - consist of capillaries and Bowman’s capsule
Function of glomerulus
Filtration - 20% of the plasma entering the glomerulus is filtered
Blood enters the glomerulus via ______ and exits via _______
Enters via afferent arteriole
Exits via efferent arteriole
Name A-I
A- afferent arteriole
B- juxtaglomerular cells
C- foot processes of podocytes
D- podocytes
E- glomerular basement membrane
F- proximal tubule
G- mesangial cells
H- extraglomerular mesangial cells
I- efferent arteriole
J- Distal convoluted tubule
Function of juxtaglomerular cells
Secrete renin - for RAAS
What triggers the release of renin
Lower perfusion in the afferent arteriole = lower blood pressure
What substances are reabsorbed at the proximal convoluted tubule
100% of glucose and amino acids
67% salt and water
What substances are reabsorbed at the proximal convoluted tubule
100% of glucose and amino acids
67% salt and water
What substances are secreted into PCT
H+
Bile
Uric acids
Drugs
Toxins
PCT is smaller / larger than DCT
Larger
Why does PCT have less well defined margins on histology than DCT
Due to presence of brush borders
Function of loop of Henle
create a hyperosmotic environment in the medulla for urine concentration and conserving water
How does hyper osmotic environment of the medulla help with urine concentration
Allows water remaining in the fluid at collecting duct to be reabsorbed hence water is conserved and also there is less water in urine = more concentrated
What is the vasa recta
the capillary network surrounding the loop of henle
Describe the osmolality in vasa recta as it goes down the descending limb and go back up in the ascending limb of loop of Henle
Osmolality rises as it dips down into the medulla (hyper osmotic medulla)
Osmolality falls as it rises up into the cortex
The blood flow to vasa recta is high / low. Why is that
low, in order to allow sufficient time for passive diffusion of solutes and water to maintain the concentration gradient in medulla (prevent washout)
Function of distal convoluted tubule
Contols acid-base and water balance
What substances are reabsorbed in DCT
water
NaCl
HCO3-
Ca2+, Mg2+, K+
What substances are secreted into DCT
H+
K+
What hormone regulates K+ excretion in DCT
aldosterone - increase in aldosterone = hypokalaemia
What hormone regulates Na+ reabsorption in DCT
Aldosterone - increase in aldosterone = more reabsorbed = hypernatraemia
Function of collecting duct
Reabsorption of water, influenced by ADH
What is the effect of ADH on collecting duct
increases permeability of collecting duct -> increase water reabsorption