Regulation of Cardiac Activity and Circulation Flashcards

1
Q

What happens to the arterial pressure as compliance decreases?

A

The systolic pressure will increase and the diastolic pressure will decrease.

The pulse pressure will widen as a result.

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2
Q

What happens to the arterial pressure as the peripheral resistance increases?

A

The systolic and diastolic pressure will both increase but the diastolic pressure will increase much more.

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3
Q

What happens to the arterial pressure as compliance increases?

A

The systolic pressure will decrease and the diastolic pressure will increase.

The pulse pressure will narrow as a result.

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4
Q

What happens to the arterial pressure as peripheral resistance decreases?

A

The systolic and diastolic pressure will both decrease, but the diastolic pressure will decrease more.

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5
Q

How does an increase in the cardiac output affect the mean arterial pressure?

A

It will increase it

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6
Q

How does an increase in the heart rate affect the mean arterial pressure?

A

It will increase the cardiac output, which will increase the mean arterial pressure.

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7
Q

How does an increase in venous return affect mean arterial pressure?

A

It will increase the cardiac output and it will increase the mean arterial pressure.

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8
Q

How does a decrease in the blood volume affect the mean arterial pressure?

A

It will lower the venous return and lower the mean arterial pressure.

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9
Q

How does anemia affect the mean arterial pressure?

A

It will lower the hematocrit, which will decrease blood viscosity and it will decrease the resistance which will decrease the mean arterial pressure.

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10
Q

How does increased metabolic activity affect the mean arterial pressure?

A

Metabolites will cause dilation of the vessels and the resistance will decrease as a result, and the mean arterial pressure will be decreased.

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11
Q

How will angiotensin affect the mean arterial pressure?

A

It will cause vasoconstriction, which will increase the resistance and increase the pressure.

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12
Q

What is the mean right atrial pressure?

A

2 mmHg

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13
Q

What is the right ventricular systolic pressure?

A

25 mmHg

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14
Q

What is the right ventricular diastolic pressure?

A

2 mmHg

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15
Q

What is the mean left atrial pressure?

A

6 mmHg

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16
Q

What is the left ventricular systolic pressure?

A

120 mmHg

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17
Q

What is the left ventricular diastolic pressure?

A

6 mmHg

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18
Q

What is the pulmonary artery pressure?

A

25/10 mmHg

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19
Q

What is the pulmonary wedge pressure?

A

6 mmHg

20
Q

What is the mean brachial artery pressure?

A

95 mmHg

21
Q

What is the mean central venous pressure?

A

5 mmHg

22
Q

Is the intrathoracic or extra thoracic venous pressure greater?

A

Extrathoracic

23
Q

Why is the extra thoracic venous pressure greater than the intrathoracic pressure?

A

The blood is coming off of the arteries which have a higher pressure than the CVP which is in the intrathoracic cavity.

24
Q

What effect does aortic stenosis have on aortic arterial pressure?

A

The aortic arterial can actually decrease due to the stenosis creating a larger pressure gradient.

Normal is 120/80 -> 110/75

25
Q

What effect does aortic stenosis have on left ventricular pressure?

A

The after load would have a massive increase and it would go up to 220/10 from the normal 115/5

26
Q

What effect does aortic stenosis have on pulmonary artery pressure?

A

It would only have a slight increase from 25/10 to 30/18

27
Q

What effect does aortic stenosis have on the central venous pressure?

A

Largely unchanged

28
Q

What effect does aortic stenosis have on heart rate?

A

It would increase the heart rate slightly going from a normal 72 to 84 due to the increased after load reduction the cardiac output. Baroreceptor reflex.

29
Q

What effect does aortic valve stenosis have on the left atrial pressure?

A

It is mostly unchanged going from 6 to 12.

30
Q

What effect does mitral valve stenosis have on arterial pressure?

A

It will decrease the arterial pressure from normal to 84/52 due to causing problems with preload.

31
Q

What effect does mitral valve stenosis have on left ventricular pressure?

A

LV pressure would decrease, especially systolic pressure, going to 87/5 because of the preload decreasing.

32
Q

What effect does mitral valve stenosis have on pulmonary artery pressure?

A

It would increase it drastically due to the mitral valve stenosis causing a back up into the artery and possibly resulting in pulmonary edema.

Pressure would go to 40/30

33
Q

What effect does mitral valve stenosis have on central venous pressure?

A

It would be largely unchanged

34
Q

What effect does mitral valve stenosis have on heart rate?

A

Heart rate would increase in order to compensate for decreased preload.

35
Q

What effect does mitral valve stenosis have on left atrial pressure?

A

It would increase it due to the backup because of the mitral valve stenosis. It would go from being around 6 to 30.

36
Q

What effect does a decrease in venous return have on arterial pressure?

A

Arterial pressure would decrease slightly but it is well tolerated.

Goes to 90/50

37
Q

What effect does a decrease in venous return have on pulmonary arterial pressure?

A

Goes to 16/8. Small change

38
Q

What effect does a decrease in venous return have on central venous pressure?

A

It would decrease significantly, falling to -2 as the veins are collapsing due to the negative pressure.

39
Q

What effect does a decrease in venous return have on heart rate?

A

Heart rate would increase in order to attempt to increase cardiac output back up to normal levels

40
Q

What effect does an increase in systemic vascular resistance have on arterial pressure?

A

It will increase both the systolic and diastolic pressure, but will increase diastolic more.

41
Q

What effect does an increase in systemic vascular resistance have on pulmonary arterial pressure?

A

It remains largely unchanged

42
Q

What effect does an increase in systemic vascular resistance have on CVP?

A

Remains unchanged

43
Q

What effect does an increase in systemic vascular resistance have on heart rate?

A

Heart rate will decrease to 45 in response to the increased pressures.

44
Q

What effect does sinus tachycardia have on the arterial and pulmonary pressures and the heart rate?

A

Heart rate increases to 120
Pulmonary Arterial Pressure has slight increase to 28/18
Arterial pressure decreases due to increased HR to 110/64

45
Q

What effect does ventricular tachycardia have on the arterial and pulmonary pressures and the heart rate?

A

HR increases to 151
PAP increases to 24/20
Arterial Pressure decreases to 82/60 due to increased HR

46
Q

What effect does ventricular fibrillation have on the arterial and pulmonary pressures and the heart rate?

A

HR 0
PAP 18/18
Arterial Pressure 19/19 - this is the mean circulatory pressure
CVP 18 - increases as blood pools in the central venous pool

47
Q

What effect does atrial fibrillation have on the arterial and pulmonary pressures and the heart rate?

A

HR 120 - HR is determined by AV node refractory period
PAP - unchanged at 25/15
Arterial Pressure is slightly decreased at 100/60 due to increased HR