Interactions between the Heart and the Peripheral Vasculature Flashcards

1
Q

What is venous return?

A

Rate at which blood returns to the thorax.

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2
Q

What is the central venous pool?

A

Volume enclosed by the right atrium and the great veins.

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3
Q

What is cardiac output?

A

Rate at which the blood leaves the central venous pool.

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4
Q

What happens to the central venous pressure as the cardiac output increases?

A

The CVP will decrease and this will increase the pressure gradient, leading to increased venous return.

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5
Q

What happens when the CVP becomes negative?

A

It will collapse the large veins of the thorax.

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6
Q

What is the systemic circulatory pressure (mean circulatory pressure [Pmc] )?

A

It is the mean pressure in the circulatory system when the cardiac output stops.

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7
Q

How do increases in blood volume change the Pmc?

A

It will increase it.

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8
Q

How do increases in venous tone change the Pmc?

A

It will increase it.

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9
Q

How do increases in the blood volume and venous tone alter the vascular function curve?

A

They will shift it up and right.

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10
Q

How does venodilation affect venous return?

A

Decreases

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11
Q

How does increased respiration (inspiration) affect venous return?

A

Increases. The negative pressure of inspiration allows the great veins to expand more and fill the RV more.

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12
Q

How does increased blood volume affect venous return?

A

Increases.

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13
Q

How does venoconstriction affect venous return?

A

Increases.

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14
Q

How does skeletal muscle contraction affect venous return?

A

Increases.

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15
Q

What is the Pcm in a normal healthy person?

A

7 mmHg

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16
Q

How does sympathetic activity affect the cardiac function curve?

A

Shifts it up and left

17
Q

How do inotropic drugs affect the cardiac function curve?

A

Shifts it up and left

18
Q

How does heart failure affect the cardiac function curve?

A

Shifts it down and right

19
Q

In cases of hemorrhage, how does the body compensate?

A

Increased sympathetic response and venous constriction.

The sympathetic response increases cardiac output while the venous constriction will increase the CVP in the body.

20
Q

In cases of heart failure, how does the body compensate?

A

Heart failure will cause a decrease in cardiac output, and so the body compensates via hypervolemia in order to raise the CVP and the cardiac output.