RBC Indices + CBC Flashcards
Ideally: Hemoglobin concentration should be three times the value of the hematocrit concentration
T or F?
F
Hematocrit dapat ang 3x higher
Which is used in hematocrit? A.Sahli’s tube B.comparator block C.wintrobe tube D.A and B E.B and C
C
Which is used in hemoglobin? A.Sahli’s tube B.comparator block C.wintrobe tube D.A and B E.B and C
D
T or F
Women are more prone to anemia than men
T
Which is not a direct cause of high Hgb level?
A. hypochromic anemia
B. decreased people living in high altitudes
C. illnesses (cancer, drug abuse)
D. smoking
A
A leads to low Hgb… Dapat erythrocytosis
The average size of red blood cells. It is the average amount of space occupied by each RBC.
Identify
Mean corpuscular volume
MCV=equal to ___ over total no. of RBC
Hemoglobin
Low MCV without anemia suggests ___
thalassemia minor (trait)
Myxedema (most severe form of hyperthyroidism) causes ___ MCV without anemia
High
Measures the variability in the size of red blood cells.
RED CELL DISTRIBUTION WIDTH (RDW)
The amount of hemoglobin in an average red blood cell.
Mean corpuscular hemoglobin
The average concentration of hemoglobin in an average RBC
Mean corpuscular hemoglobin concentration
Which is not true?
A.Increased reticulocytes (reticulocytosis) is a normal response to blood loss or anemia.
B.Since reticulocytes are larger, the MCV (and RDW) may be decreased.
C.Anemia combined with a low or normal reticulocyte count indicates that the bone marrow is unable to respond normally.
B
Elevated dapat. Not decreased
Increased destruction of RBC may cause any of ff except: A.Aplastic anemia B.Spherocytosis C.Hemoglobin disorders D.Hemorrhage (blood loss) E.Hypersplenism
A
Hemolytic dapat
Low MCV + low RDW = __
Thalassemia minor
The oxygen-carrying capacity protein ___ contains iron, and gives blood its red color
heme
Which is not a possible cause + (other condition) of megaloblastic anemia?
A.vitamin deficiency (usually B12 or folic acid)
B.alcohol intake (moderately high levels)
C.leukemia (WBCs do not have to be abnormal too)
C
WBC has to be abnormal
Identify
vitamin B12 deficiency caused by an inability to absorb the vitamin from the GI tract. May cause neuropathy, weakness, or even psychiatric problems
Pernicious anemia
Identify
A condition where the immune system attacks and destroys RBCs
Autoimmune histolytic anemia
The two forms of autoimmune histolytic anemia are ___ & ___
Warm antibody and Cold Agglutinin disease
Both types of autoimmune histolytic anemia cause Normocytic anemia with antibodies against RBCs.
What kind of test is this? Also: (+) or (-) ba
positive Coomb’s test
Anemia is only for acute inflammation. True or false?
False
Inherited disorders of the globin gene leading to low levels of alpha or beta globin chains
Identify
Thalassemias
- Typically mild anemia with marked microcytosis
- Can coexist with other hemoglobin abnormalities, with increased severity of the anemia and increased mortality concern, but ___) has no excess mortality concerns
Identify trait
BETA THALASEMMIA MINOR
Identify Hb disorder
- large variety of genetic disorders which affect the biosynthesis of heme (all are rare)
- May cause episodes of severe abdominal pain, sensitivity to sunlight, even psychiatric problems or paralysis
Porphyria
Possible causes of Neutrophilia
Common: bacterial infections, inflammatory disorders, stress, certain drugs, pregnancy
Rare: __
Leukemia
Possible causes of Neutropenia Common: chronic benign neutropenia, chemotherapy
Rare: __ & __
SLE & Immunodeficiency
True or false: for leukocytosis and neutropenia, Treatment is usually aimed at the underlying cause
True
Chronic benign neutropenia - which is false?
A.Overall risk of infection is high, but usually asymptomatic
B.Two forms: familial and non-familial C.Key features from underwriting perspective are the absence of significant infections and stability over time
A
Low dapat
gives important information about the kinds and numbers of cells in the blood, especially RBC, WBC and platelets
Complete Blood Count
