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PH 156 > RBC Abnormalities > Flashcards

RBC Abnormalities Flashcards

1
Q 
Rouleaux Formation:short/long stacks of RBC. Seen in all except:
A.Hyperproteinemia 
B.Atypical pneumonia
C.Multiple Myeloma (MM) 
D.Pregnancy
A

B

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2
Q 
autoagglutination is commonly seen in the ff except \_\_?
A.hemolytic anemia
B.Mycoplasma pneumonia
C.staphylococcal infections
D.schistosomiasis
A

D

Trypanosomiasis dapat

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3
Q

variation in Hb content is also called as __

A

Anisochromia

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4
Q 
Hypochromia is commonly seen in all except
A.iron deficiency anemia
B.rheumatoid arthritis
C.acute infections
D.inflammation
A

C

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5
Q 
False about hyperchromic blood
A. Lacks central pallor, blood is too bright red
B. Seen in sickle cell anemia
C. Spherocytes may be detected
D. true state if MCV is elevated
A

D

MCHC dapat

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6
Q

Macrocytic RBC is not seen in
A.B1 deficiency
B.Alcoholism, without liver disease C.Cancer chemotherapy
D.Chronic hemolytic anemia

A

A

B12 dapat

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7
Q

Megaloblastic anemia associated with achlorydia and lack of intrinsic factor necessary for the binding and absorption of vitamin B12.

Identify!

A

Pernicious anemia

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8
Q

RBC is thinner than normal and have colorless center (increased surface area, not proportional to the volume)

Identify

A

Leptocytes

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9
Q 
Where are leptocytes not seen?
A.thalassemia
B.obstruction of pancreatic ducts
C.cirrhosis
D.steatorrhea
A

B

Bile dapat

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10
Q

Variation in shape, abnormal shape of cells

Identify

A

Poikilocytosis

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11
Q

Not a direct cause of poikilocytosis
A.structural changes in the cell membrane
B.A metabolic state in the cell C.Hemoglobin molecule abnormality
D.Person’s age

A

D

Red cell age dapat

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12
Q

Identify

Cell with irregular, long, assymettrical projections; specially seen with severe liver disease or post-splenoctomy; seen with rare disorder of abetalipoprteinemia

A

Acanthocyte

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13
Q

Identify

Similar to ring forms of malaria

A

Babesiosis

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14
Q

Identify

Small aggregates of RNAs are seen as small blue dots in the RBC;

A

Basophilic stippling

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15
Q

Elongated, elliptical cell; non-specific when occasionally seen; rare hereditary disorder

Identify

A

Elliptocyte

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16
Q

Identify

Precipitated Hgb seen as a perimembranous blue dot only after supravital staining, seen with some hemoglobinopathies

A

Heinz body

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17
Q

Identify

Small, round deeply basophilic nuclear remnant; seen when spleen is absent

A

Howell-Jolly body

18
Q

Cells with decreased MCH, typical of iron deficiency

Identify

A

Hypochromia

19
Q

Cells with increased MCH, typical of megaloblastic anemia

A

Macrocytic

20
Q

Plasmodium infection seen as ‘ring forms’, stippling and gametocytes, depending upon the species

Identify

A

Malaria

21
Q

Cells with decreased MCV, typical of iron deficiency anemia and thalassemia

A

Microcytosis

22
Q

Multiple, tiny iron-containing granular blue dots; seen when spleen is absent and with iron overload

Identify

A

Pappenheimer body

23
Q

Variation in shape of RBCs

A

Poikolicytosis

24
Q

The bluish tint to young RBCs with high RNA content

A

Polychromatophilia

25
Q

Identify

Young RBCs with increased RNA content that can be precipitated by supravital staining for identification and enumeration

A

Reticulocyte

26
Q

Identify

Linear aggregation of RBCs that resembles stack of coins; when surface charge is reduced with increased serum protein, particularly increased fibrinogen or globulin

A

Rouleaux

27
Q

Identify

Non-nucleated RBC with stainable iron

A

Sideroblast

28
Q

Identify

Small, round dense cell without central pallor; suggests extravascular (splenic) hemolysis in previously normal persons;

A

Spherocytes

29
Q

with hereditary spherocytosis there is increased osmotic fragility

T or F

A

T

30
Q

Fragmented, irregularly shaped seen with intravascular hemolysis such as microangiopathic hemolytic anemias (DIC, TTP);

Identify

A

Schistocyte

31
Q

Identify

Curved, banana-shaped cell with pointed ends found in sickle cell disease from aggregation of Hgb S

A

Sickle cell

32
Q

Cell with slit-like central pallor;

Identify

A

Stomatocyte

33
Q

Cell with central and peripheral staining with intervening pallor due to increased redundancy of RBC membrane; seen with liver disease, in some thalassemias and with high Hgb C

Identify

A

Target cell

34
Q

Cell pinched at one end, prominent in myelofibrosis and myelophthisic conditions

Identify

A

Teardrop cell

35
Q 
Ovalocytes may be seen in:
A. Sickle cell anemia
B. Thalassemia
C. autoimmune hemolytic anemia 
D. microangiopathic hemolytic anemia
A

A and B

36
Q 
Spherocytes may be seen in:
A. Sickle cell anemia
B. Thalassemia
C. autoimmune hemolytic anemia 
D. microangiopathic hemolytic anemia
A

C and D

37
Q

False about echinocytes
A. caused by release of substances from glass that changes pH and transform cells into echinocytes
B. In stored blood - increase of ATP and biochemical abnormalities in plasma
C. Not normally seen in vivo
D. Regarded as an artifact

A

B

Decrease dapat

38
Q

Identify:
• spicules may be irregularly shaped, unevenly spaced
• Seen in renal insufficiency
• If seen in PBS should be reported

A

Burr cell

39
Q

A.Caused by changes in the ratio of plasma lipids (lecithins and sphingomyelins)
B. Have irregularly spaced, few pointed spicules or thornlike projections of various lengths and widths to club shaped
C. Hereditary and acquired

Identify the abnormal RBC

A

acanthocyte

40
Q

Identify RBC abnormal cell

  • Elongated, with slit like area of pallor • Hereditary or acquired
  • May be a result of high cellular sodium and low potassium content
  • May be retained in the spleen because of abnormality
A

Stomatocyte

41
Q

Identify RBC abnormal cell

  • Central area of Hb surrounded by colorless ring and a peripheral ring of Hb
  • Always acquired (No hereditary)
  • Membrane surface is increased because of cholesterol and phospholipid loading
  • Seen in THALASSEMIA
A

Codocyte

42
Q 
Serum - Plasma minus \_\_\_\_
A. Fibrinogen
B. Thrombin
C. WBC
D. RBC
A

A

PH 156 (13 decks)

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