RBC Abnormality Vocab Flashcards

0
Q

What species is rouleaux common in?

A

Horses and dogs

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1
Q

What do you often see with roleaux?

A

Increased fibrinogen or serum globulin levels

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2
Q

What species is roleaux rare in?

A

Ruminants

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3
Q

When can rouleaux be exaggerated?

A

During inflammatory or neoplasticism disease

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4
Q

What is agglutination?

A

Clumping of RBC

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5
Q

When does agglutination occur?

A

Sometimes in antibody mediated anemia

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6
Q

How can you differentiate roleaux from agglutination?

A

Dilute with saline 1:1, roleaux will separate, agglutination will stay clumped

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7
Q

What do polychromasia RBC look like?

A

Bluish cytoplasm, resembles residual DNA

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8
Q

What is hypochromasia?

A

Decreased staining intensity, increased central pallor

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9
Q

What is the most common cause of hypochromasia?

A

Iron deficiency

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10
Q

Where will you see poikilocytosis?

A

In diseases characterized by RBC fragmentation or increased fragility, liver kidney, spleen, vessel problems

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11
Q

What are leptocytes?

A

Thin cells with increased membrane and decreased hemoglobin volume.

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12
Q

What cells are easily folded and distorted?

A

Leptocytes

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13
Q

What are leptocytes common in?

A

Non regenerative anemias

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14
Q

What are two of the most common types of leptocytes?

A

Target cells and folded cells

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15
Q

What are target cells?

A

Look like target signs, small number is normal.

16
Q

When will you see target cells?

A

Iron deficiency and hepaticocyte insufficiency

17
Q

What are target cells aka?

A

Consulted

18
Q

What are folded cells aka?

A

Knizocytes

19
Q

What do spherocytes look like?

A

Small dark RBC lacking central pallor.

20
Q

What causes spherocytes?

A

Reduction of membrane

21
Q

What species are spherocytes readily detected?

A

Dogs

22
Q

What are three things that can auss spherocytes?

A

AIHA, zinc toxicity, following transfusion

23
Q

What are stomatocytes?

A

Cup shaped RBC that look like lips

24
Q

What do stomatocytes indicate?

A

Certain liver diseases

25
Q

What breed of dog has hereditary stlmatocytes?

A

Alaskan malamutes

26
Q

What are acanthocytes or spur cells?

A

Irregular spoculated RBC

27
Q

How many blunt projections will be on a acanthocytes?

A

2-10

28
Q

What do acanthocytes mean?

A

Severe liver disease, increased blood cholesterol, hemangioma archons, DIC, glomerulonephitis

29
Q

What are schistocytes?

A

Irregularly shaped fragments of RBC sheared into pieces

30
Q

What is microangiopathy disease?

A

Partial occlusion of vessels forcing cells through

31
Q

What are echinocytes?

A

Crenated or spiculated

32
Q

What can cause echinocytes?

A

Increased EDTA, improper smear prep, or prolonged sample storage.