Lymphocytes Flashcards

1
Q

What is an antigen?

A

substence that triggers specific immune response when present in the body

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2
Q

what is an antibody?

A

specialized protien production in response to an antigen

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3
Q

what are the five classes of Ab? (IgGAMED)

A

IgG, IgM, IgE, IgA, IgD (GAMED)

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4
Q

what is IgG and IgM?

A

for bacteria and viruses

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5
Q

what is IgE?

A

Allergic responses

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6
Q

what is IgA?

A

protect Gi, urogenital, respiritory tracts

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7
Q

what is IgD?

A

present on surfaces of B-Lumphs and initiate humoral immune response

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8
Q

What happens when an Ag stimulates a B-Lymph?

A

the B-lymph divedes or transforms into cells that produce Ab

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9
Q

what do lymphocytes look like?

A

round cell with large round dark purple nucleus with smooth margins and very little blue cytoplasm

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10
Q

what are two types of lymphocytes?

A

T lymph and B lymphs

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11
Q

What do T lymphs do?

A

they actively kill effected cells or stimulate inflammation to attract neutrophils

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12
Q

what is cell mediated immunity?

A

the T cells control immunity

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13
Q

do T cells secrete ab/

A

no

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14
Q

What are T lymphs

A

they have Ag receptors on their bodies so they can recognize and react to other Ag and are effective to other cells with Ag on them. It gives a specific immune response to the intracellular phase of a viral infection, fungi, parasites, or bacteria.

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15
Q

What are B-Lymphs?

A

they deal with humoral immunity which deals with ab in the blood, plasma, and lymph

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16
Q

what do B lymphs do?

A

they see a Ag and create plasma cells and memory cells. the plasma cells with create antibodies to combat the Ag while the memory cells remember the Ab and save it for later.

17
Q

where do memory cells live?

A

in the lymph nodes

18
Q

how long does it take for the immune response to build up?

A

7-10 days

19
Q

how long does the memory cell stage take?

A

24-48 hours

20
Q

where will Ab go when they are produced?

A

they will circulate as a free gamma globulin protien in plasma until they combine with a specific Ag and neutralize it. a Eosinophil will then come eat it.

21
Q

How many lymphocytes will appear in the blood stream?

A

10%

22
Q

where do lymphocytes like to hang out?

A

lymphnodes, spleen and liver

23
Q

Where do T-Cells come from?

A

from stem cells in red bone marrow and travel via the blood stream to the Thyamus gland to mature. T for Thymus

24
Q

where do B cells come from?

A

from stem cells in the red bone marrow and travel via the blood stream to the liver, spleen, lymph nodes

25
Q

how long are lymphnodes normally in the blood stream?

A

30 minutes

26
Q

what are antigenicity stimulated lymph?

A

immunocytes larger/more intense cytoplasmic color with a dark purple rim on the cell membrane and somtimes with a golgi zone

27
Q

what is the golgi zone?

A

clear perinuclear zone on Ig

28
Q

which species have small lymphocytes with blue cytoplasm and in rare cases red cytoplasmic inclusions?

A

dogs

29
Q

what species is simular to dogs but the nucleus can be slightly indented and no cytoplasmic inclusions?

A

cats

30
Q

which species has lymphocytes straight up simular to dogs?

A

horses

31
Q

which species has lymphocytes as the predomininant WBC. small in size and can have larger cells with alot of cytoplasm, indented nucleus, and pink/lavendar cytoplsmic inclusions?

A

bovine.

32
Q

what are lymphoblasts?

A

large lymphs which contain nucleoli.

33
Q

what are plasma cells?

A

rare in blood, eccentrically placed around nucleus with a pale perinuclear area