Random UWorld Flashcards

1
Q

Sotalol

A

Class III anti-arrythmic (block K+ channels as well as b-blocker)

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2
Q

action of cilostizol and dipyridamole

A

Direct vasodilators and prevent platelet aggregation

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3
Q

arsenic poisoning rx

A

dimercaprol

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4
Q

Class switching to IgE via

A

IL-4

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5
Q

eosinophil activation via

A

IL-5

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6
Q

IgA class switching via

A

IL-5

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7
Q

calcipotriene =

A

vitD analog. can use to treat psoriasis

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8
Q

excessive MMP and fibroblast activity in wound =

A

contracture

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9
Q

HBs =
HBc =
HBe =

A
HBs = envelope = previous status/immunity
HBc = nucleocapsid core = current status
HBe = precore/core = infectivity
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10
Q

postural hypertension

A

Conn’s

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11
Q

Nuclei and NTs

A
Raphe = 5HT
Ceruleus = NE
Meynert = Ach
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12
Q

MRSA rx, MOA, AE

A

Vanco:

  • blocks D-ala D-ala
  • Nephrotoxicity, ototoxicity, red-man

Daptomycin:

  • disrupts PM altering electrolytes
  • myopathy/rhabdo increasing CK, inactivated by surfactant

Linezolid:

  • binds 50s preventing initiation complex
  • Thombocytopenia, peripheral neuropathy, serotonin syndrome
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13
Q

Biotin use

A

CARBOXYLASES!

  • pyruvate carboxylase: pyruvate to OAA
  • acetyl coA carboxylase; acetyl coA to malonyl coA
  • propionyl coA carboxylase: propionyl coA to methylmalonyl coA
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14
Q

rhabditiform larvae in stool

A

strongyloides

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15
Q

Lyme rx

A

doxycyclin or penicilin-type Abx

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16
Q

layer directly around fetus

17
Q

pH that ppts renal stones

A

All @ low pH .: CD

EXCEPT struvite stones (NH4-Mg-PO4)

18
Q

anesthetic solubility directly proportional to:

A

blood:gas coefficient

19
Q

MC antidepressants to ppt mania

A

TCAs

Venlafaxine (SNRI)

20
Q

thiazide AE

A

HYPER-GLUC

21
Q

What receptors does NE work on

A

a1, a2, b1

22
Q

lowest O2 content vessel

A

coronary sinuses

23
Q

oral nitrate

A

isosorbide mononitrate

24
Q

first aortic arch

A

maxillary artery

25
second aortic arch
stapedial a. | hyoid a.
26
third aortic arch
common carotid | proximal internal carotid
27
fourth aortic arch
``` R = proximal subclavian L = aortic arch ```
28
sixth aortic arch
proximal pulmonary arteries | L = ductus arteriosus
29
Rx peripheral arterial disease
cilostazole | Inhibits PDE, causing direct vasodilation and prevents platelet aggregation (by decreasing cAMP)
30
alpha blockers
phentolamine (rev) | phenoxybenzamine (irrev.)
31
nitrates cause
large vein dilation [dilate arteries with a1 blockers]
32
LPLase defic. risk of:
acute pancreatitis
33
what does the nucleolus do
makes rRNA (with RNA pol I) and assembles ribosomes
34
trachea movements and lung lesions
Towards = atelectasis or simple pneumothorax Away = tension pneumothorax or large pleural effusion