Random UWorld Flashcards

1
Q

Sotalol

A

Class III anti-arrythmic (block K+ channels as well as b-blocker)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

action of cilostizol and dipyridamole

A

Direct vasodilators and prevent platelet aggregation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

arsenic poisoning rx

A

dimercaprol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Class switching to IgE via

A

IL-4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

eosinophil activation via

A

IL-5

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

IgA class switching via

A

IL-5

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

calcipotriene =

A

vitD analog. can use to treat psoriasis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

excessive MMP and fibroblast activity in wound =

A

contracture

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

HBs =
HBc =
HBe =

A
HBs = envelope = previous status/immunity
HBc = nucleocapsid core = current status
HBe = precore/core = infectivity
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

postural hypertension

A

Conn’s

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Nuclei and NTs

A
Raphe = 5HT
Ceruleus = NE
Meynert = Ach
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

MRSA rx, MOA, AE

A

Vanco:

  • blocks D-ala D-ala
  • Nephrotoxicity, ototoxicity, red-man

Daptomycin:

  • disrupts PM altering electrolytes
  • myopathy/rhabdo increasing CK, inactivated by surfactant

Linezolid:

  • binds 50s preventing initiation complex
  • Thombocytopenia, peripheral neuropathy, serotonin syndrome
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Biotin use

A

CARBOXYLASES!

  • pyruvate carboxylase: pyruvate to OAA
  • acetyl coA carboxylase; acetyl coA to malonyl coA
  • propionyl coA carboxylase: propionyl coA to methylmalonyl coA
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

rhabditiform larvae in stool

A

strongyloides

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Lyme rx

A

doxycyclin or penicilin-type Abx

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

layer directly around fetus

A

amnion

17
Q

pH that ppts renal stones

A

All @ low pH .: CD

EXCEPT struvite stones (NH4-Mg-PO4)

18
Q

anesthetic solubility directly proportional to:

A

blood:gas coefficient

19
Q

MC antidepressants to ppt mania

A

TCAs

Venlafaxine (SNRI)

20
Q

thiazide AE

A

HYPER-GLUC

21
Q

What receptors does NE work on

A

a1, a2, b1

22
Q

lowest O2 content vessel

A

coronary sinuses

23
Q

oral nitrate

A

isosorbide mononitrate

24
Q

first aortic arch

A

maxillary artery

25
Q

second aortic arch

A

stapedial a.

hyoid a.

26
Q

third aortic arch

A

common carotid

proximal internal carotid

27
Q

fourth aortic arch

A
R = proximal subclavian
L = aortic arch
28
Q

sixth aortic arch

A

proximal pulmonary arteries

L = ductus arteriosus

29
Q

Rx peripheral arterial disease

A

cilostazole

Inhibits PDE, causing direct vasodilation and prevents platelet aggregation (by decreasing cAMP)

30
Q

alpha blockers

A

phentolamine (rev)

phenoxybenzamine (irrev.)

31
Q

nitrates cause

A

large vein dilation

[dilate arteries with a1 blockers]

32
Q

LPLase defic. risk of:

A

acute pancreatitis

33
Q

what does the nucleolus do

A

makes rRNA (with RNA pol I) and assembles ribosomes

34
Q

trachea movements and lung lesions

A

Towards = atelectasis or simple pneumothorax

Away = tension pneumothorax or large pleural effusion