Radiation Enterocolitis and Solitary Rectal Ulcer Disease

Question 1

What are the effects of RTx on the colon?

Answer 1

Damage to epithelium/endothelium, decreased mitoses, and villous shortening

Question 2

Hallmakr of solitary rectal ulcer syndrome?

Answer 2

Smooth muscle proliferation from the muscularis mucosae into the lamina propria