Congenital Disorders of the Large Intestine

Question 1

What does segmental absence of ganglion cells cause?

Answer 1

Congenital megacolon (Hirschprung DIsease)

Question 2

What condition is associated with a greater rate of Hirschsprung disease?

Answer 2

Down Syndrome

Question 3

Most common cause of congenital intestinal obstruction?

Answer 3

Hirschsprung Disease

Question 4

What part of the GI system is typically constricted in Hirschsprung Disease?

Answer 4

Typically the most distal part is constricted, and then depending on the how far ganglion cells migrated in development, you move proximally.