Radiation Colitis Flashcards

1
Q

How can radiation affect the intestine

A

Abdominal exposure to radiation can cause defects in the normal proliferative activity of the epithelium in the small and large intestine

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2
Q

Symptoms

A

Anorexia
Abdominal cramping
Diarrhoea
Malabsoprtion

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3
Q

What does RC mimic

A

IBD

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4
Q

Histology

A
Inflammation 
Crypt abscesses
Eosinophils 
Ulceration 
Haemorrhage
Perforation 
Necrosis
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5
Q

Which cells does radiation target

A

Actively dividing cells

  • Especially blood vessels and crypts
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