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E - GI > Gastric Cancer > Flashcards

Gastric Cancer Flashcards

1
Q

Usually, what kind of cancer is gastric cancer

A

Adenocarcinoma

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2
Q

Presentation

A 
Dyspepsia 
Weight loss
GI bleeding 
Anaemia
Gastric Outlet Obstruction
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3
Q

Causes

A

Genetics
Smoking
H. Pylori
Diet

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4
Q

Pathological types

A 
Intestinal = associated with H. pylori associated gastritis, atrophy and intestinal metaplasia, causing adenoma to form 
Diffuse = also associated with H. pylori but without atrophy or intestinal metaplasia, leads to poorly differentiated cancer with a poor prognosis
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5
Q

Genes associated with hereditary diffuse gastric cancer

A

CDH-1 (E-cadherin)

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6
Q

Management

A
  1. Biopsy to confirm diagnosis histologically
  2. CT chest / abdo to stage cancer
  3. MDT meeting
  4. Treatment - surgery or chemo
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E - GI (47 decks)

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