quiz 6 Flashcards
hormone-producing tissue
mostly glands
-pancreas
endocrine system
message delivery system
hormones
molecules that deliver a message inside a target cell
target cells
cells that a hormone communicates with
Non steroid hormone communication
binds to receptor on the exterior cell membrane
-stimulates a secondary messenger
-cAMP - secondary messenger
-glucagon outside the cell
non lipid soluble
cannot cross a membrane
-made from amino acids
-require cell surface receptors
non steroid hormones are separated into 2 groups
protein and amino acid derived hormones
protein/peptide hormones
made from a string of amino acids
-insulin, glucagon, growth hormone
amino acid derived hormone
thyroid hormones (T3 and T4)
-adrenal hormones
-catecholamines (adrenaline)
steroid hormones are made from
cholestrol
lipid soluble steroid hormones
diffuse through membranes
examples of steroid hormones
adrenal hormones (cortisol)
sex hormones (estrogen, progesterone, and testosterone
homeostasis and feedback
- stimulus
- receptor
- control center
- effector
- stimulus reduced
blood sugar
body wants it to be between 70-100 mg/dl
hyperglycemic
high blood sugar
-insulin
-pancreas senses and releases insulin to lower blood sugar
hypoglycemic
low blood sugar
-glucagon
-pancreas senses and releases glucagon raises blood sugar
a primary role of the endocrine system is to maintain the body homeostasis
- blood sugar
- body temp
- metabolism
- blood calcium
- blood pressure
- hydration
negative feedback loop:
increased output from system inhibits system output
-increases output from the system decreases deviation in homeostasis, enabling homeostasis
- stimulus
homeostasis deviation from set point or range
- sensor
thermostat temperature sensor
-hypothalamus
- control center
thermostat controls trigger of furnace
-hypothalamus
- effector
furnace/air conditioner producing hot or cold air
- restoring temperature to
set point or range
moe hormones =
usually means “greater action”
hormone action dependent on
amount of working receptors
receptor amount can change due to
upregulation and down regulation
upregulation
increase number of receptors
moe receptors = greater action
sensitization
desensitization
decrease number of receptors
fewer receptors = less action
desensitization
steroid hormone receptors found
inside cell, cytoplasm or nucleus
hormone receptor complex enters nucleus and
binds to DNA, which regulates mRNA synthesis (transcription and translation)
nonsteroid hormones receptors are found
on cell membrane (need second messengers)
carry out hormone effects inside cells and delivers message via
second messenger
common second messengers
cAMP
exercises ___ secretion of all anterior pituitary hormones
increases
GHRH releases
GH
stimulating hypothalamus
GHRH
growth hormone releasing hormone
higher intensity causes greater release of
GH
GH is an _____ hormone
anabolic hormone
GH stimulates fat metabolism via
lipolysis
thyroid gland releases
T3 and T4