Quiz 1 Flashcards
_________________ uses ATP to pump sodium out and potassium into the cell
active transport
What is the concentration gradient of the cell
- sodium outside
- potassium inside
what is the electrochemical potential difference of the cell
Negative -70mv
- more positive outside
- more negative inside
____________ the balancing of the forces of charge and concentration gradient
electrochemical gradient
___________ is the axon used in the experiment. It is unmylinated and very thick
giant squid axon
What are the three steps of an action potential
- depolarization
- repolarization
- hyperpolarization
_____________________ sodium channels open allowing sodium to flow in and increase membrane potential to about +40 mv
depolarization
___________________ potassium channels open because of strong positive, allowing membrane potential to return to its negative value
depolarization
______________ sudden decrease to potassium equilibrium (-93 mv) and then a slow return to -70mv via sodium potassium pump
hyper polarization
Hodkins and huskily used a ____________ to mimic depolarization to determine the shape of the conducted atoms and amounts of what is exchanged
voltage clamp
During depolarization sodium permeability rose to a peak and then returned to zero potassium rose but did not inactivate
depolarization
_________________ block sodium channels
tetrodotoxin
_________ blocks potassium channels
tetraethyl Ammonium
Why are ion channels able to discriminate agains singling charged ions
- size: molecules must be less than 3A
- oxygen lining: only molecules that can make hydrogen bonds can pass
- can remove their water shell
The introduction of chemicals allowed the scientists to measure
what molecules (sodium and potassium) enter and leave the cell during an action potential