Muscle Module 7 Flashcards

1
Q

Smooth muscle is _______________

A

not as specialized as skeletal muscle

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2
Q

3 key feature of smooth muscle cells

A
  • there is a SR Membrane in smooth muscle
  • No T tubules
  • No neuromuscular junction
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3
Q

Why dont we need T tubules in smooth muscle cells

A

T tubules conduct depolarization in action potential deep in the cell but smooth muscle cells are small

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4
Q

Without neuromuscular junctions what happens to the path of neurotransmitters in cell

A

neurotransmitters have a larger distance to travel and thus the smooth muscle has a slower response to stimulus

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5
Q

Where does the sarcoplasmic reticulum lay in smooth muscle

A

no myofibrils so it lays at the membrane

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6
Q

Skeletal muscle from a teleological perspective.

A

Designed go produce large force rapidly thus

  • contractile units are parallel to each other
  • neurtransmitter have a short area of diffusion
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7
Q

____________ explains a phenomena in terms of the purpose it serves

A

teleology

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8
Q

Smooth muscle from a teleologic al perspective although the contraction relies on CA2+ cross bridges too contract;

A

however, the physiological design is very varied to acomidate for various functions

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9
Q

Smooth muscle filaments

A

smooth muscle has thin and thick filaments variable in length

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10
Q

________________ is more varied in smooth muscle than skeletal muscle

A

length and organization of filaments

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11
Q

sarcoplasmic reticulum lays at the membrane because

A

smooth muscle has no myofibrils

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12
Q

adjacent demosomes allow the cells to

A

mechanically connect

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13
Q

____________ are specialized structures at the cell membrane that thin filaments attach to. Their function is to allow thin filaments to attach to cell membrane

A

demosomes

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14
Q

dense bodies connect __________________

A

adjacent thin filaments.

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15
Q

dense bodies have a composition similar to _________

A

Z disks

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16
Q

__________ site where two cells are in chemical continuity with one another so small molecules can pass from one smooth muscle cell to another.

A

Gap junction

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17
Q

Gap junctions allow smooth muscle cells to be in

A

electrochemical continuity

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18
Q

Where are smooth muscles typically located

A

walls of hallow organs, blood vessels, airways, GI system

19
Q

what is the side of an organ that is lined with hallow muscle called

A

lumen

20
Q

What is the connective tissue laying between the lumen and smooth muscle called

A

endothelium

21
Q

What are the cl;assifications of smooth muscle based on contraction

A
  • phasic

- tonic

22
Q

______________ are the relatively break and synchronous contractions including the beginning of esophagus

A

phasic

23
Q

__________ are the relatively slow and prolonged contractions

A

tonic

24
Q

what are some of the causes for the variability in smooth muscle contraction

A
  • variability in neurotransmitters (stimulatory or inhibitory)
  • variability in proximity of neuron
  • variability in distribution of receptors for NT
  • contractility in endocrine regulated (ex hormones)
  • variability in density of voltage gated channels
  • variabilty ion cell communications
25
Q

skeletal muscle only has ______________

A

excitatory neurotransmitters

26
Q

what is one way that makes smooth muscle cell communications unique

A

Gap Junctions which sharer electrochemical information

27
Q

What is the classification of smooth muscle by organization

A
  1. multiunit

2. single unit

28
Q

______________ is characterized by

  • fine control and over contraction
  • prolongued contraction
A

multiunit

29
Q

_______________ is characterized by

  • rythmic contraction
  • uniform contraction
A

single unit

30
Q

example multiunit smooth muscle

A

blood vessels, airways

31
Q

example multiunit smooth muscle

A

blood vessels, airways

-very fine control of controlling the muscles

32
Q

example single smooth muscle

A

uterus, intestine

-0rythmic centurion necessisarry to deliver a baby

33
Q

Examples of tonic muscles

A
  • esopophagus sphincter, arteries
  • maintain finetuning
  • 0tend to be multiunit
34
Q

examples of phasic muscles

A
  • intestine, uterus
  • rhythmic, rapid
  • teend to be single unit
35
Q

________ graded response, no action potential

A

multiunit smooth muscle allows this to happen

36
Q

why are phasic muscles typically single unit

A

gap junctions and action potentials

37
Q

_____________ are receptors for neurotransmitter and are less than in skeletal muscle cells

A

ligand gated channels

38
Q

________________ for circular factors. CLosser to blood vessels where blood is released

A

ligand gated channel for circulating factors

39
Q

__________ are low in number and some are calcium channels for contraction

A

voltage gated channels

40
Q

Why aren’t action potentials produced by multiunit smooth muscle

A

low number of voltage gated Ca2++ ions

41
Q

What kind of response are produced by multiunit smooth muscle

A

a little bit of contraction for a relatively brief period of time in a select # of cells operating independently. Because each cell is independent, we can either get a little contraction or ra lot of contraction

42
Q

Are action potentials produced by single unit smooth muscle

A

yes because more voltage gated ion channels

43
Q

do single unit smooth m muscle cells have gap junctions

A

yes gap junctions

44
Q

explain the response of single unit smooth muscle

A

all or none response. Rapid synchronous, depolarized and contraction