Questions On Lecture Four

Question 1

What is something strange related to acuate phasreactant

Answer 1

Is the influx of neutrophil because in acute phase response the g-csf is increased in production

Question 2

A distinctive something about NK cells

Answer 2

That they are able to kill infected cells without prior sensitization

Question 3

What is the most important cytokine in allergy and what is the cytokines that is considered chymokine

Answer 3

Il4 and il8

Question 4

When they say to u which complement protein is not involved consider the following as always involved because they are a common pathway so involved at all

Answer 4

C3 c6-9

Question 5

Which of the following diseases affect the neutrophils
And read the note

Answer 5

Chronic granulomatous disease
Note :the هذيك الصبغة the blue one affect and get a dark color for the normal neutophil that has no nadph deficiency so hydrogen peroxide is produced it is what get that dark color

Question 6

What is the molecules that is functionally same as membrane attack complex

Answer 6

Perforins in nk cells

Question 7

What is the cause of autoimmune lymphploripherative syndrome

Answer 7

Mutation in fas gene (in adcc of the nk cells)

Question 8

Which is the enzymatic part of the c3 convertase of the alternative pathway

Answer 8

C3 convertase is c3bBb it is the factor b

Question 9

An example of a pattern recognition molecule

Answer 9

Collections (Mbl)

Question 10

Interferons type one mainly affect(not the cell but the pathogen)

Answer 10

Virusis (هوه بطلع ضد الvirally infected cells)

Question 11

Deficiency of early c3 complement causes

Answer 11

Systemic lupus erthmatosous (SLE)

Question 12

Give me an example of a complement that act as
Chemotactic factor
As opsinon

Answer 12

C3a c4a c5a
C3b c3dg

Question 13

What is the order in strength of the anaphylatoxins

Answer 13

C5a>c3a>c4a

Question 14

In the clearance of the immune complex which of the following helps the RBcs in that

Answer 14

The c3b and c4 complement
Also the receptor is cr1

Question 15

Note that cd16

Answer 15

Is the same as fc gamma r111
That is the nk cell receptor
There is an other receptor that is for the mast cell fce r1

Question 16

What is the protein released in the acuate phase response in viral and bacterial infection

Answer 16

C reactive protein

Question 17

Interferons do something strange which is

Answer 17

Induce the production of enzymes in the target cell

Question 18

What is the particle that is a connection between adaptive and innate immunity
And what is the particle that makes the early response to viral infection in innate immunity

Answer 18

Cytokines
Interferons

Question 19

Nk cells can be activated by the interferons that they produce the gamma interferon

Answer 19

True

Question 20

The most important function of igm in responses is to

Answer 20

Is to make complement activation

Question 21

Low level of c3 in blood for an ill child mean he was suspectibal to

Answer 21

Recurrent bacterial infection
Because c3 should be dominant in plasma

Question 22

Does the respiratory burst have a phagolysosome fusion

Answer 22

No

Question 23

When a tissue is injured what is the first thing that will occur

Answer 23

Cytokines released

Question 24

What is the type of granules In the neutrophils

Answer 24

Microbial granules

Question 25

What is the if that works against the worms

Answer 25

Ige