Questions On Lecture Four Flashcards
What is something strange related to acuate phasreactant
Is the influx of neutrophil because in acute phase response the g-csf is increased in production
A distinctive something about NK cells
That they are able to kill infected cells without prior sensitization
What is the most important cytokine in allergy and what is the cytokines that is considered chymokine
Il4 and il8
When they say to u which complement protein is not involved consider the following as always involved because they are a common pathway so involved at all
C3 c6-9
Which of the following diseases affect the neutrophils
And read the note
Chronic granulomatous disease
Note :the هذيك الصبغة the blue one affect and get a dark color for the normal neutophil that has no nadph deficiency so hydrogen peroxide is produced it is what get that dark color
What is the molecules that is functionally same as membrane attack complex
Perforins in nk cells
What is the cause of autoimmune lymphploripherative syndrome
Mutation in fas gene (in adcc of the nk cells)
Which is the enzymatic part of the c3 convertase of the alternative pathway
C3 convertase is c3bBb it is the factor b
An example of a pattern recognition molecule
Collections (Mbl)
Interferons type one mainly affect(not the cell but the pathogen)
Virusis (هوه بطلع ضد الvirally infected cells)
Deficiency of early c3 complement causes
Systemic lupus erthmatosous (SLE)
Give me an example of a complement that act as
Chemotactic factor
As opsinon
C3a c4a c5a
C3b c3dg
What is the order in strength of the anaphylatoxins
C5a>c3a>c4a
In the clearance of the immune complex which of the following helps the RBcs in that
The c3b and c4 complement
Also the receptor is cr1
Note that cd16
Is the same as fc gamma r111
That is the nk cell receptor
There is an other receptor that is for the mast cell fce r1
What is the protein released in the acuate phase response in viral and bacterial infection
C reactive protein
Interferons do something strange which is
Induce the production of enzymes in the target cell
What is the particle that is a connection between adaptive and innate immunity
And what is the particle that makes the early response to viral infection in innate immunity
Cytokines
Interferons
Nk cells can be activated by the interferons that they produce the gamma interferon
True
The most important function of igm in responses is to
Is to make complement activation
Low level of c3 in blood for an ill child mean he was suspectibal to
Recurrent bacterial infection
Because c3 should be dominant in plasma
Does the respiratory burst have a phagolysosome fusion
No
When a tissue is injured what is the first thing that will occur
Cytokines released
What is the type of granules In the neutrophils
Microbial granules
What is the if that works against the worms
Ige
