Lec Three Flashcards
What is the fist recirculating pathway
The traveling of lymphocyte from blood to tissue to lymph node
هذا يوضح انه اولاً الlymphocyte تتاكد من وجود الAg في العقد الليمفاوية بعدين بتعمل recirculating
Note a misunderstanding about recirculation
Recirculation mean
يصل يلفلف على كل الجسم مش بس بال lymph and blood vessels
Note a misunderstanding about recirculation
Recirculation mean
يصل يلفلف على كل الجسم مش بس بال lymph and blood vessels
Important note about how the lymphocyte get out of the hev to the lymph node
It get by adhesion like homing and the extravasation it isn’t draining
Who release the chymokines and why
Macrophages if there’s inflammation for T cells to come there
In general to allocates the lymphoma to their allocated area in the secondary lymphoid organs
The peripheral lymph node hev and they are ccl17 ccl21 to bind to the ccr7 on the surface of dendritic cells and lymphocyte
Lfa 1 and a4b6 are integrins
Right
Where’s most naive T cells activations occur
In the secondary lymphoid organ
حتى اكثر من ال infected tissue لأنه الأساس يلاقوا الضد تاعهم في الsecondary lymphoid organ
Cxcr1 bind to what
Il8
S1p is what
Is lipid mediator and not a cytokines help the lymphocytes to get out of the lymph node
Chemotaxis is what
Is a directed movement of cells toward tissue by the help of cytokines and it is according to the chemical gradient
Is oral tolerance an adaptive immunity
It’s a bridge between innate and adaptive immunity
What do we mean by receptor editing
It’s maturation development and specification
What will occur if the platelets activating factor paf bind to its receptor on the neutrophil
Gonna activate the express of the LFA1
What does il7 do
Help in the proliferation of lymphocyte in the primary lymphoid organs
What is wrong and what is right
Macrophage monocytes system is all from monocyte deravitive wrong على الرغم انه ال macrophage جاية من monocyte
All of the progenitor and stem cells look the same under macroscope right
