Lecture Rwo Flashcards
What is the type of igs on the mucosa (on the lumenail surface of the the epithelial cell)
Immunoglobulin type A
What do we mean by immune system suppression
That my immune system does not work against that antigen doesn’t fight it o if it is a forgein harmless body then that is good but if it was a harmful antigen then if an immune suppression occurs toward it ,this antigen gonna enter the body and give me harmful effects
What would happen if an immune suppression occurred toward hepatitis b virus
It is going to enter my body and my immune system will not fight it then it is going to go toward the liver and causes hepatoma hepatitis and chirosis
Could you explain why we should not take more than three doses in a vaccine
What is the vaccine it’s giving a mild or dead pathogen to our bodies (pathogen harmful body) then we give it through doses so we make more antibodies and memory cells against that antigen but if these doses succeed the three doses an immune suppression is going to occur toward that pathogen and thus it will enter the body and no immune responses towards it so it will make harmful effects toward my body
How the desensitization occur
It is in order to treat an allergy (which my immune system make immune responses toward a foreign harmless material because the suppressor cells did not do their function well by suppressing the immune system toward it ) so we give multiple frequent doses of that material to my body so my immune system will be suppressed toward that body and thus make no response toward it
What is the region in the bone marrow that get us growth factors and cytokines
Reticular stroma and it helps in the hamatopiosis
What is the region in the bone marrow that get us growth factors and cytokines
Reticular stroma and it helps in the hamatopiosis
Mention the maturation region according to the cell
T lymphocyt the cortex of thymus
B lymphocyte the bursa fabursic of the bone marrow
Other myeloid cells the marrow enviroment
And it is not just maturation but also specification and development
Where is the hassell corpuscle
In the thymus for the dead negative selected celss
What is the George syndrome
It is the lost of the third pharyngeal pouch
Thus no thymus gland thus deficiency in the cell mediated immunity
No parathyroid gland thus tetany
If thymoectomy occur what will happen
Nothing bad
Because the pool of the lymphocyte will be maintained by just the proliferation of the mature one on the periphery by the help of I’ll-7
If thymoectomy occur what will happen
Nothing bad
Because the pool of the lymphocyte will be maintained by just the proliferation of the mature one on the periphery by the help of I’ll-7
The ag comes toward the ln by the lymph vessels
The lymphocyte comes toward the lymph node by the Hev high epithelial Venice that drain directly to the paracortex
Right
Right
Describ histology ally all of the following
Thymus
Ln
Spleen
Thymus subcapsular cortex medulla about selection
Ln cortex b para cortex T medulla both with macrophages
Spleen white pulp pals T follicles b red pulp macrophage eating the tensile red blood cells
Talk about thymoectomy and spleenoectomy
No problem with thymoectomy because the peripheral pool of lymphocyte is maintained by the proliferation of the mature cells by il 7
But the spleenectomy is hard because the spleen lodge 25 percent of the lymphocyte and it’s so important for the thymus independant immunity so there is a risk of geting infection out of the encapsulated bacteria their ag is polysaccharide so need thymus independant immunity so w should congegted vaccine protein and polysaccharide against them and prophylactic antibiotics
