Questions from S 4 Flashcards

1
Q

Actual exam question

How do these viral infections present?

Rift Valley Fever

Eastern Equine Encephalitis

Western Equine Encephalitis

Venezuelan Equine Encephalitis

St Louis Encephalitis

A

Rift Valley Fever - Flu-like illness, visual disturbance due to macula disease, encephalitis, haemorrhagic fever

Eastern Equine Encephalitis - Flu-like illness, encephalitis

Western Equine Encephalitis - Flu-like illness, encephalitis

Venezuelan Equine Encephalitis - Flu-like illness, encephalitis

St Louis Encephalitis - Flu-like illness, encephalitis

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2
Q

Actual exam question

What is the case fatality rate of these infections?

Rift Valley Fever

Eastern Equine Encephalitis

Western Equine Encephalitis

Venezuelan Equine Encephalitis

St Louis Encephalitis

A

Rift Valley Fever - 1%. And that is usually the 1% of total cases which end up developing haemorrhagic fever. 90% if <1 year old

Eastern Equine Encephalitis - 40-80 - different reports vary

Western Equine Encephalitis - 10%

Venezuelan Equine Encephalitis - <1%

St Louis Encephalitis - 5-20%

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3
Q

Which groups of people are most at risk of severe disease from these infections?

Rift Valley Fever

Eastern Equine Encephalitis

Western Equine Encephalitis

Venezuelan Equine Encephalitis

St Louis Encephalitis

A

Exposure to mosquitoes - outdoor workers

Most infections cause very mild asymptomatic disease. Very young or very old seem more prone to developing encephalitis

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4
Q

What are the vectors for these infections

Rift Valley Fever

Eastern Equine Encephalitis

Western Equine Encephalitis

Venezuelan Equine Encephalitis

St Louis Encephalitis

A

All mosquitoes

Rift Valley Fever - Aedes/ Culex

Eastern Equine Encephalitis - Culex

Western Equine Encephalitis - Culex

Venezuelan Equine Encephalitis - Culex

St Louis Encephalitis - Culex

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5
Q

What is the case fatality rate for these infections?

West Nile Virus

Japanese Encephalitis

Yellow Fever virus

Dengue virus

A

West Nile Virus - 3-15% if encephalitis develops. But <1% develop symptoms

Japanese Encephalitis - 30% if encephalitis develops

Yellow Fever virus - 3%, but 20% if severe complications develop

Dengue virus - <1% with treatment. 25% in severe untreated Dengue

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6
Q

Which Bunyaviridae are arboviruses?

A

Rift Valley Fever

Toscana
Sandfly fever - Naples/ Sicilian

Severe fever with Thrombocytopenia virus
CCHF

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7
Q

How are these Bunyaviridae arboviruses transmitted?

Rift Valley Fever

Toscana
Sandfly fever - Naples/ Sicilian

Severe fever with Thrombocytopenia virus
CCHF

A

Culex mosquito
Rift Valley Fever

Sandfly
Toscana
Sandfly fever - Naples/ Sicilian

Hard ticks
Severe fever with Thrombocytopenia virus
CCHF

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8
Q

Which Flaviviridae are arboviruses?

A

Dengue
Zika
Yellow fever
West Nile
St Louis
Japanese Encephalitis
Murrary Valley

Omsk haemorrhagic fever
Kyasanaur Forest disease
Tick borne encephalitis
Powassan

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9
Q

How are these Flaviviridae arboviruses transmitted?

Dengue
Zika
Yellow fever
West Nile
St Louis
Japanese Encephalitis
Murrary Valley
Omsk haemorrhagic fever
Kyasanaur Forest disease
Tick borne encephalitis
Powassan

A

Mosquito Aedes
Dengue
Zika
Yellow fever

Mosquito Culex
West Nile
St Louis
Japanese Encephalitis
Murrary Valley

Hard Tick
Omsk haemorrhagic fever
Kyasanaur Forest disease
Tick borne encephalitis
Powassan

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10
Q

Which Togaviridae are arboviruses?

A

Chikungunya
Venezuelan equine encephalitis
Sindbis
Western Equine Encephalitis virus
Eastern Equine Encephalitis virus

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11
Q

How are these Togaviridae arboviruses transmitted?

Chikungunya
Venezuelan equine encephalitis
Sindbis
Western Equine Encephalitis virus
Eastern Encephalitis virus

A

Aedes mosquito
Chikungunya

Culex mosqutio
Venezuelan equine encephalitis
Sindbis
Western Equine Encephalitis virus
Eastern Encephalitis virus

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12
Q

What is geographic distribution of these viruses?

Western Equine Encephalitis virus
Eastern Equine Encephalitis virus
Venezuelan Equine encephalitis

A

Western Equine Encephalitis virus - North America/ South America

Eastern Equine Encephalitis virus - North America/ South America

Venezuelan Equine encephalitis - Central/ South America

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13
Q

What is the primary host of these arboviruses? (not dead end host)

Dengue
JEV
Rift Valley fever
West Nile virus
TBEV
Yellow Fever

A

Dengue - humans/ primates

JEV - pigs/ birds

Rift Valley fever - bats

West Nile virus - birds

TBEV - small rodents

Yellow Fever - primates

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14
Q

What is the primary host of these arboviruses?

Eastern Equine Encephalitis

Western Equine Encephalitis

Venezuelan Equine Encephalitis

St Louis Encephalitis

A

Birds are main hosts. Horses are dead-end hosts
Eastern Equine Encephalitis
Western Equine Encephalitis
Venezuelan Equine Encephalitis

Birds are main host
St Louis Encephalitis

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15
Q

How does West Nile virus present?

A

Flu-like illness

Encephalitis

Acute flaccid paralysis

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16
Q

Patient presents with fever, cough, SOB, visual disturbance, and then develops encephalitis

What infection to suspect?

A

Rift Valley Fever -

Flu-like illness
visual disturbance due to macula disease
encephalitis
spontaneous haemorrhage