QTC

Question 1

Normal QTC for men

Answer 1

<440

Question 2

Normal QTC for women

Answer 2

<470

Question 3

Metabolic risks for QTC prologation

Answer 3

low calcium, low Mg, low potassium

Question 4

Antipsychotic with highest effect on QTC

Answer 4

Pimozide

Question 5

Antipsychotics with moderate effect on QTC

Answer 5

haloperidol, quetiapine, chlorpromezine, amisulpride, ziprasidone

Question 6

Antipsychotics with low effect on QTC

Answer 6

clozapine, olanzapine, risperidone, aripiprazole, palperidone

Question 7

Antipsychotic with no effect on QTC

Answer 7

lurasidone

Question 8

SSRI that effects QTC

Answer 8

citalopram, ecitalopram

Question 9

Antidepressants that can affect QTC

Answer 9

citalopram, ecitalopram, tricyclics, trazadone

Question 10

Other non-psychotropic drugs that can affect QTC (antibiotics)

Answer 10

erythromycin, ampicillin

Question 11

Other non-psychotropic drugs that can affect QTC (cardiac)

Answer 11

amiodarone, sotalol

Question 12

Other non-psychotropic drugs that can affect QTC (anti malarial)

Answer 12

chloroquine, quinine

Question 13

Other non-psychotropic drugs that can affect QTC (other)

Answer 13

methadone, tamoxifen, amantadine

Question 14

What is the QT interval

Answer 14

measured from the beginning of the QRS complex to the end of the T wave and approximates the time it takes the ventricles to repolarize

Question 15

What is Bazzett’s formula

Answer 15

QTcB = QT / RR 1/2

Question 16

What is Torsades de Pointes and what is the rate?

Answer 16

A polymorphic ventricular tachycardia. Its rate varies from 160 to 240 and tends to be slower than ventricular fibrillation.