HSV encephalitis

Question 1

peripheral lesions (e.g. cold sores) have no relation to presence of HSV encephalitis true or false

Answer 1

true

Question 2

Which type of HSV responsible for 95% of cases in adults

Answer 2

HSV 1

Question 3

CSF in HSV ?

Answer 3

lymphocytosis, elevated protein

Question 4

CT findings in HSV

Answer 4

medial temporal and inferior frontal changes (e.g. petechial haemorrhages) - normal in one-third of patients

Question 5

EEG findings in HSV

Answer 5

lateralised periodic discharges at 2 Hz

Question 6

What is prognosis dependent on in HSV

Answer 6

whether aciclovir is commenced early.
If treatment is started promptly the mortality is 10-20%. Left untreated the mortality approaches 80%

Question 7

Features of HSV encephalitis

Answer 7

fever, headache, psychiatric symptoms, seizures, vomiting
focal features e.g. aphasia