Dementia Flashcards
1
Q
How do ACh inhibitors work?
A
prevent cholinesterase from breaking down acetylcholine.
2
Q
How does memantine work?
A
NMDA receptor antagonist that blocks the effects of pathologically elevated levels of glutamate that may lead to neuronal dysfunction.
3
Q
How does galantamine work?
A
AChE-I (competitive + reversible), and Nicotine receptor agonist
4
Q
How does rivastigmine work?
A
AChE-I (reversible + non-competitive)
5
Q
How does donepezil work?
A
AChE-I (selective + reversible)
6
Q
What percent AIDS patients get dementia
A
50%
7
Q
atrophy of frontal and temporal lobes is also known as
A
Pick’s disease
