Q2 INTEGUMENT Flashcards
layer of the epidermis (deep to superficial)
stratum basale, spinosum, granulosum, lucidum, corneum
Follicular ostia
Skin pore
What type of gland are sebaceous
Holocrine
What type of gland are sweat glands
Apocrine or eccrine based on hair vs non-hair
Orthokeratosis
Nuclei absent
Parakeratosis
Nuclei present
Spongiosis
Intracellular edema
Acantholysis
Disruption of desmosomes between keratinocytes (usually immune mediated)
Granulation tissue
Capillaries and fibroblasts perpendicularly orientated
Furunculosis
Rupture of the hair follicle
Hidradentitis
Apocrine gland inflammation
Photosensitization types
1: primary ingestion of photodynamic substance
2: inherited enzyme deficiency
3: hepatogenous disease causes phylloerythin to accumulate in the blood
Pithomycotoxicosis
Ovine facial eczema caused by build up of mycotoxins
Dry gangrene (fescue foot)
Ergotamine and ergovaline causes vasoconstriction and ischemic necrosis of the hind legs
Acral lick dermatitis
Psychogenic hyperplastic dermatitis on the extremities
Acral lick dermatitis
Psychogenic hyperplastic dermatitis on canine extremities
Intertrigo
Skin fold dermatitis with retained moisture creates a great environment for bacteria
Poxviridae
Mechanical vectors, eosinophilic inclusion bodies
Ex. Swine pox, orf, lumpy skin disease
Papillomaviridae
Benign epithelial proliferation then enters stratum basale
Superficial pyoderma
Heals without scarring, no lymph node involvement, epidermis, epidermal collarettes (impetigo, greasy pig disease)
Deep pyoderma
Hair follicle, dermis, and hypodermis affected, draining tracts and regional lymphadenitis/ furunculosis
Which bacteria produce septic embolism and vasculitis near the skin?
E. rhusiopathiae, salmonella, and E. coli, all produce toxins
which viral diseases mimic bacterial toxins?
porcine dermatitis and nephropathy syndrome (PDNS), african swin fever, and classical swine fever
dermatophytosis
ringworm!! could be trichophyton or microsporum, furunculosis, intracorneal microabscesses
pythiosis
swamp cancer, limbs of animals/ water mould
sporotrichosis
dermatitis and lymphangitis (zoonotic)
demodicosis
in hair follicle (mange if immune compromised)
scabies/ notoedric mange
ears, head, neck, zoonotic
psoroptic mange
sheep scabs, external ear canals and body
chorioptic mange
back end of horse and ruminants
equine cutaneous habronemiasis
summer sores, spread by flies
onchocerca infection
ventral midline of horses
urticaria
hives
atopic dermatitis
IgE type 1, secondary infections with staph and malassezia
insect bite hypersensitivity
immune type 1 and 4
pemphigus foliaceus
type 2, targets desmoglein-1, intragranular pustules
pemphigus vulgaris
type 2, targets desmoglein 1 and 3, suprabasilar vesicles, oral lesions
bullous pemphigoid
targets hemidesmosomal proteins, very red lesions, mostly subbasilar clefts
lupoid onychitis
type 3, claw sloughing then regrowth of misshapen claw, biopsy needs nailbed epithelium
systemic lupus erythematosus
type 3, ab in skin BM and lymphohistiocytic dermatitis with subepidermal vesicles
discoid lupus erythmatosus
photosensitive nasal dermatitis
what can cause depigmentation in ruminants
copper deficiency
pityriasis rosea
pigs 3-14 weeks old, resolves spontaneously, crusts groin
puppy strangles
juvenile sterile granulomatous dermatitis and lymphadenitis of puppies under 4 months
canine zinc responsive dermatosis
huskies, decreased intestinal absorption of Zn, scales and plaques, parakeratosis
endocrine alopecia causes
hypothyroidism, hyperadrenocorticism, hyperestrogenism, hypersomatotropism, hyposomatotropism
plasma cell pododermatitis
cats MT/MC pads swollen with white streaking