PVD 1 Flashcards

1
Q

Localized abnormal dilatations of blood vessels due to vessel weakness; may occur in cardiac chamber; defined as at least a 50% increase in diameter of a vessel

A

Aneurysm

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2
Q

Aneurysm that is bounded by complete but dilated vessel wall components is considered a (true/false) aneurysm; atherosclerotic, syphilitic, congenital

A

True

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3
Q

Aneurysm that involves an extravascular hematoma that communicates with the intravascular space is considered a (true/false) aneurysm; pulsating hematoma

A

False

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4
Q

A fusiform aneurysm is shaped like a…

A

oval parallel to the long axis

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5
Q

A saccular aneurysm is shaped like a…

A

bubble-like outpouching

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6
Q

A dissecting aneurysm is

A

blood passing through a tear in the intima into the tunica media (separates the vessel wall layers)

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7
Q

An aneurysm associated with syphilis is usually located in the.

A

ascending aorta

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8
Q

An aneurysm associated with cystic media degeneration is usually located in the

A

ascending/thoracic aorta

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9
Q

An aneurysm associated with atherosclerosis is usually located in the

A
abdominal aorta
muscular arteries (coronary, popliteal)
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10
Q

Difference between Atherosclerosis and Aneurysm (in regards to inflammation)

A

Atherosclerosis: inflammation on intima
Aneurysm: inflammation on adventitia

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11
Q

AAA is always associated with severe

A

atherosclerosis and mural thrombosis

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12
Q

Aneurysm caused by bacterial infection

A

mycotic aneurysm

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13
Q

Type of AAA with dense periaortic (around aorta) fibrosis and inflammation caused by lymphocytes, macrophages, etc.

A

Inflammatory aneurysms

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14
Q

Autosomal dominant connective tissue disorder with fibrillin-1 defect; fragmented elastic fibers in aortic media and valves; high incidence of valve regurgitation, vessel dissection and rupture; tall, slender, thin extremities, long fingers, kyphosis

A

Marfan syndrome

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15
Q

Congenital syndrome with type III procollagen defect; arteries are as fragile as tissue paper

A

Type IV Ehlers-Danlos Syndrome

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16
Q

Atherosclerotic plaques commonly occur at…

A

bifurcations (like carotid artery)

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17
Q

Blood passing from the aortic lumen through a tear in the intima into the tunica medica then propagates in a FALSE LUMEN

A

Aortic dissection

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18
Q

Two groups predisposed to aortic dissection

A
  1. Men, 40-60 years old, History of HTN

2. Connective Tissue Disorders (Marfan syndrome)

19
Q

Most frequent preexisting lesion in those with aortic dissection is

A

cystic medial degeneration

*CMD (cystic spaces within tunica media with loss of SMC and elastin, instead filled with ECM); common in Marfan syndrome

20
Q

What is the major risk factor of Aortic Dissection?

21
Q

Aortic dissection in ascending (proximal) aorta is categorized as (type A or B)

22
Q

Aortic dissection in descending (distal) aorta is categorized as (type A or B)

23
Q

Which type of aortic dissection is more common and dangerous thus needs early, urgent surgical management? (Type A or B)

A

Type A (can affect coronary arteries and valves)

24
Q

Arterial thrombosis are most commonly occurs on_____ while venous thrombosis are most commonly due to

A

atheromas/plaque; stasis (stoppage of blood flow)

25
Virchow's Triad for predisposition to thrombosis
1. Changes in blood components 2. Endothelial dysfunction 3. Changes in blood flow (stasis)
26
Common sites for arterial thrombosis
1. Large/medium muscular arteries (aorta, carotid, coronary) | 2. Intracardiac
27
defined as the passage through the arterial or venous circulation of any material capable of lodging in a vessel and obstructing the lumen (air, amniotic fluid, thrombus)
Embolism
28
Venous thrombosis are typically located in
Deep veins (legs, pelvic)
29
Symptoms of DVT
1. Frequently asymptomatic 2. Calf tenderness (associated Homan sign) 3. Congestion, edema, cyanosis
30
Source of arterial emboli are usually
cardiac mural thrombus
31
Most frequent thromboemboli
PE
32
Most common source of PE
DVT
33
Massive PE is associated with acute failure in
right heart
34
arterial thrombosis is rich in what?
platelets * treat arterial thrombosis with anti-platelet
35
venous thrombosis is rich in what?
fibrin * treat venous thrombosis with anticoagulant
36
Aortic dissection may reenter aortic lumen forming
double barreled aorta
37
The main cause of death for aortic dissection is
extravascular rupture
38
What is a characteristic of thrombi that appear more when formed in arteries than veins?
Lines of Zahn
39
Dark bands in lines of zahn indicate
RBCs
40
Light bands in lines of zahn indicate
fibrin and platelets
41
When coagulation occur on the injured site, it is called
thrombus
42
When thrombus gets dislodge somewhere else, it is called
embolus
43
AAA has ____morphologic dilatation
fusiform