Pulmonary Therapeutics Flashcards
A plug in the mainstem bronchus that obstructs airflow with collapse of affected lung tissue
atelectasis
The filling of alveoli with fluid or blood cells
consolidation
Chest condition characterized by a disturbance in ventilation due to decreased chest wall or lung movement
Restrictive
3 main symptoms associated with asthma
dyspnea
wheezing
cough
% improvement during the pre/post-bronchodilator challenge that represents reversible airway obstruction
> 12%
Normal FEV1/FVC ratio
> 75%
Normal FEV1
> 80%
Normal FVC
> 80%
FEV1/FVC ratio that normally represents restrictive lung disease
> 88%
FEV1/FVC ratio that normally represents obstructive lung disease
% of predicted DLco that is considered abnormal
The protein responsible for the hydolysis of membrane phospholipids, releasing arachidonic acid
Phospholipase A2
3 cysteinyl leukotrienes
LTC4, LTD4 and LTE4
Enzyme that catalyzes arachidonic acid to cysteinyl leukotrienes
lipoxgenase
An antiprotease deficiency that leads to risk of COPD
alpha-1 antitrypsin deficiency