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P&T > Anxiety therapeutics > Flashcards

Anxiety therapeutics Flashcards

0
Q

Most common co-morbid disorder associated with SAD

A

psychiatric disorder

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1
Q

Minimum length of time of persistent worry or changes in behavior necessary to qualify as panic disorder

A

1 month

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4
Q

Number of symptoms associated with panic attack needed to qualify as panic disorder

A

4

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5
Q

Major co-morbidity associated with panic disorder

A

agoraphobia

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7
Q

Min. length of fear of social situation needed to qualify as SAD

A

6 months

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8
Q

Minimum length of anxiety/worry to qualify as generalized anxiety disorder

A

6 months

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9
Q

Min. length of symptoms needed to qualify as PTSD

A

1 month

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11
Q

4 AEs of SSRIs/SNRIs

A
  1. nausea
  2. sleep disterbances
  3. sexual dysfunction
  4. headache
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12
Q

Score on GAD-7 that indicates moderate GAD

A

10-14

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13
Q

SSRI that is not as effective as others for treatment of panic disorder

A

citalopram

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14
Q

TCA that has been shown to be effective in treating OCD (1st line)

A

clomipramine

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17
Q

3 adverse effects of buspirone

A
  1. Nausea
  2. Dizziness
  3. Headache
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18
Q

Time to response in treatment of PTSD

A

8-12 weeks

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19
Q

The 2 best studied TCAs in treatment of anxiety

A
  1. Imipramine

2. Clomipramine

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20
Q

Score on GAD-7 that indicated severe anxiety

A

> 15

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21
Q

Symptoms of GAD (need at least 3 to qualify for diagnosis)

A
  1. restlessness
  2. fatigue
  3. sleep disturbances
  4. irritability
  5. muscle tension
  6. difficulty concentrating
22
Q

3 preferred BZDs in active liver disease

A
  1. Lorazepam
  2. Oxazepam
  3. Temazepam
23
Q

4 treatments that are NOT effective in treating panic disorder

A
  1. propanolol
  2. buspirone
  3. antihistamines
  4. antipsychotics
24
Q

Type of psychotherapy specific for SAD

A

exposure therapy

25
Q

Length of therapy for SAD

A

usually long-term

26
Q

3 treatments NOT effective in treating SAD

A
  1. TCAs
  2. buspirone monotherapy
  3. atenolol
27
Q

Adjunctive therapy that has evidence in OCD patients that don’t respond to SSRI (2nd line)

A

Mirtazapine

28
Q

Timing of max effect of buspirone

A

4-6 weeks

29
Q

Min length of therapy for GAD

A

12 months

30
Q

Min length of therapy for PTSD

A

at least 12 months after response

31
Q

Class of medications that can decrease perception of anxiety in performance-only SAD

A

Beta-blockers (propanolol or atenolol)

32
Q

Alpha-1 antagonist that may decrease nightmares and insomnia in PTSD

A

Prazosin

33
Q

The gold standard screening tool for GAD

A

Hamilton Anxiety Scale

34
Q

3 treatments that are not effective in treating PTSD

A
  1. buspirone
  2. bupropion
  3. desipramine
35
Q

Time to see response for GAD

A

2-4 weeks to effect and 4-6 weeks to full effect

37
Q

Length of therapy for OCD

A

Min. 1-2 years, usually lifelong

38
Q

3 best options for treating anxiety in pregnancy

A
  1. citalopram
  2. fluoxetine
  3. sertaline
39
Q

Time to response in treating OCD

A

10-12 weeks

40
Q

Length of therapy for panic disorder

A

12-24 months

41
Q

Length of medication trial that should be used for SAD

A

8-12 weeks

44
Q

Time to response in panic disorder

A

6-12 weeks and at least 2 weeks at current dose

45
Q

alpha-2 agonist that may be used to treat PTSD

A

Clonidine

47
Q

Score on GAD-7 that indicated mild GAD

A

5-9

50
Q

Min length of time after event for full diagnostic criteria to be met to qualify as PTSD with delayed expression

A

6 months after event

P&T (18 decks)

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