Pulmonary embolism Flashcards

1
Q

What type of embolism is a pulmonary embolism?

A

Thromboembolism

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2
Q

Where does the thrombus usually arise from in pulmonary embolism?

A

Deep vein in leg

particularly the popliteal vein, iliac veins

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3
Q

What is the name of the condition of a thrombus in a deep vein in the leg?

A

Deep vein thrombosis (DVT)

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4
Q

How does a small pulmonary embolism present?

A

Asymptomatic

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5
Q

How do multiple small pulmonary emboli present?

A

Pulmonary hypertension

Right ventricular failure

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6
Q

Why do multiple small pulmonary emboli cause pulmonary hypertension?

A

Block pulmonary arteries

increases pressure in pulmonary arteries

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7
Q

Why do multiple small pulmonary emboli cause right venticular failure?

A

Right ventricle has to contract harder to generate higher pressures to push blood through pulmonary circulation
suffers volume overload

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8
Q

How do large pulmonary emboli present?

A

Pleuritic chest pain

Dyspnoea

Pleural rub

Raised JVP

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9
Q

What investigations are done when a patient is suspected to have a pulmonary embolism?

A

Chest X-ray

ECG

Blood gases

D-dimer

CT scan

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10
Q

What does a chest X-ray of a patient with a pulmonary embolism look like?

A

Normal

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11
Q

What does an ECG of a patient with a pulmonary embolism look like?

A

Right chest leads - T wave inversion

S1 Q3 T3

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12
Q

What is S1 Q3 T3?

A

Lead 1 - deep S wave

Lead 3 - deep Q wave, inverted T wave

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13
Q

What are the levels of blood gases of a patient with a pulmonary embolism?

A

Hypoxia

Hypocapnia

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14
Q

Why do patients with pulmonary embolism have hypocapnia?

A

Respiratory alkalosis

due to hyperventilation

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15
Q

What are the levels of D-dimers in the blood of a patient with a pulmonary embolism?

A

Patient who’s never had a pulmonary embolism before - raised

Patient who’s had a pulmonary embolism before - normal or raised

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16
Q

How are pulmonary embolisms treated?

A

For all patients, oxygen immediately

For all patients, IV heparin immediarely

Only for high risk patients

  • fibrinolytics
  • thrombectomy, embolectomy

For all patients, oral anticoagulents or IVC filter long-term

17
Q

How does immediate IV heparin treat a pulmonary embolism?

A

Stops the propogation of the thrombus in the pulmonary artery and also the source

18
Q

What are some examples of fibrinolytics?

A

Streptokinase

Tissue plasminogen activator

19
Q

How are fibrinolytics given?

A

IV

directed to pulmonary artery embolism by a percutanenous catheter

20
Q

What is an example of an oral anticoagulant?

A

Warfarin

21
Q

How long are patients who had a pulmomary embolism given oral anticoagulants for?

A

3 months if there was an identifiable risk factor

Forever if there was no identifiable risk factor, or if they have cancer

22
Q

What is an IVC filter?

A

Filter in the IVC that presents the passage of thromboemboli from the lower body up to the heart

23
Q

When is an IVC filter given to a patient who had a pulmonary embolism?

A

If they can’t be given anticoagulants

24
Q

What is a paradoxical embolus?

A

Embolus passes from right atrium, through patent foramen ovale, into left atrium

25
Q

What does a paradoxical embolus most commonly cause? How?

A

Stroke

travels from left atrium to blood vessel supplying the brain

26
Q

How does a pulmonary embolism affect ventilation:perfusion?

A

Causes ventilation:perfusion mismatch

because alveoli are ventilated but not perfused

27
Q

What is a saddle embolus?

A

Pulmonary embolism that lodges in the bifurcation of the pulmonary artery