Histology of the respiratory system Flashcards

1
Q

What are the parts of the respiratory tract?

A

Conducting part

Respiratory part

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2
Q

What is meant by the conducting part of the respiratory tract?

A

Air passes through here

but no gas exchange occurs

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3
Q

What are the actual conducting parts of the respiratory tract?

A

Nasal cavity

Pharynx

Larynx

Trachea

Bronchi

Terminal bronchioles

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4
Q

What is meant by the respiratory part of the respiratory tract?

A

Where gas exchange takes place

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5
Q

What are the actual respiratory parts of the respiratory tract?

A

Respiratory bronchioles

Alveolar ducts

Alveolar sacs

Alveoli

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6
Q

What covers the surface of the nasal cavity?

A

Mucosa

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7
Q

What are the different types of mucosa in the nasal cavity?

A

Nasal mucosa

Olfactory mucosa

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8
Q

Where are the nasal and olfactory mucosa located in the nasal cavity?

A

Olfactory mucosa is located in the superior posterior region of the nasal cavity

Nasal mucosa is located everywhere else

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9
Q

What type of epithelium lines the nasal mucosa?

A

Pseudostratified ciliated epithelium

Goblet cells

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10
Q

What is the function of goblet cells in the nasal mucosa?

A

Produce mucus

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11
Q

What is the function of mucus in the nasal cavity?

A

Trap particles, bacteria etc.

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12
Q

What is the function of the cilia in the nasal mucosa?

A

Beat

waft mucus containing particles, bacteria etc. down to oropharynx to be swallowed

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13
Q

What does the lamina propria of the nasal mucosa contain?

A

Serous glands, mucous glands

Lots of blood vessels

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14
Q

What is the function of the mucous glands in the nasal mucosa?

A

Secrete mucus

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15
Q

What is the function of the serous glands in the nasal mucosa?

A

Secrete watery substance

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16
Q

What is the function of the watery substance secreted by the serous glands in the nasal mucosa?

A

Humidify the inspired air

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17
Q

What is the function of the rich blood supply of the nasal mucosa?

A

Warms the inspired air

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18
Q

How does the olfactory mucosa compare to the nasal mucosa?

A

Contains olfactory neurons

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19
Q

What is the function of the olfactory neurons?

A

Special sensory - smell

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20
Q

What is the wall of the trachea made up of?

A

Mucosa

Submucosa

Hyaline cartilage

Adventitia

21
Q

What type of epithelium lines the mucosa of the trachea?

A

Pseudostratified ciliated epithelium

Goblet cells in between

22
Q

What is significant about the basement membrane of the epithelium of the trachea?

23
Q

What does the submucosa of the trachea contain?

A

Seromucous glands

Trachealis muscle

24
Q

What is the function of the seromucous glands in the submucosa of the trachea?

A

Secrete watery-mucus substance

25
What is the function of the hyaline cartilage in the trachea?
Prevent collapse of the trachea during inspiration
26
What shape is the hyaline cartilage of the trachea?
C shaped rings
27
How does the trachealis muscle relate the C-shaped rings of hyaline cartilage?
Trachealis muscle joins the free ends of the C-shaped rings
28
What is the function of the smooth muscle outside of the lamina propria in the primary bronchi?
Contracts to give bronchoconstriction Relaxes to give bronchodilation
29
How do the walls of the primary bronchi compare to the wall of the trachea?
Primary bronchi have layer of smooth muscle outside of lamina propria In primary bronchi, the hyaline cartilage forms a complete circle, not C-shaped
30
How do the walls of the secondary and tertiary bronchi compare to the walls of the primary bronchi?
In secondary and tertiary bronchi, the hyaline cartilage forms a crescent shape, not a complete circle
31
How do the walls of terminal bronchioles compare to the walls of secondary and tertiary bronchi?
Terminal bronchiole has simple ciliated columnar epithelium, Clare cells, no goblet cells Terminal bronchiole has no seromucous glands in its submucosa Terminal bronchiole has no cartilage
32
How do the walls of respiratory bronchioles compare to the walls of terminal bronchioles?
Respiratory bronchioles have simple cuboidal epithelium
33
What is the function of Clara cells?
Produce surfactant
34
Why are there no seromucous glands and goblet cells in the terminal bronchioles?
Bronchioles have narrow lumen | mucus would narrow the lumen, close the lumen
35
If the walls of terminal bronchioles have no cartilage, how are they held open during inspiration?
By the pull of the surrounding alveoli
36
What is an alveolar sac?
Air space which many alveoli open into
37
What is an alveolar duct?
Airway which many alveoli open into
38
What are the walls of alveoli made up of?
Simple squamous epithelial cells Macrophages Pulmonary capillaries Elastic and reticular fibres
39
What are the types of simple squamous epithelial cells lining alveoli? Which is more common?
Type 1 pneumocytes - more common Type 2 pneumocytes
40
What is the function of type 1 pneumocytes in the alveoli?
Gas exchange
41
What is the function of type 2 pneumocytes in the alveoli?
Produce and secrete surfactant
42
What lies between the pneumocytes and the pulmonary capillaries?
Basement membrane of both the endothelium of the pulmonary capillaries and of the pneumocytes fused together as one
43
How are the type 2 pneumocytes differentiated from the type 1 pneumocytes?
Type 2 pneumocytes contain lamellar bodies
44
What are lamellar bodies of type 2 pneumocytes?
Vesicles containing surfactant
45
What happens to the lamellar bodies of type 2 pneumocytes?
Exocytosed
46
What is the function of the macrophages of the alveoli?
To phagocyose particles or bacteria in the alveoli
47
How does the lumen of the respiratory tract change as you go down the tract?
Decreases in diameter
48
How does the thickness of the walls of the respiratory tract change as you go down the tract?
Decrease in thickness