Psychotic disorders Flashcards
Gender for Schizophrenia
M=W
Role of socioeconomic status in Schizophrenia
-higher prevalence in lower classes
what age is onset of schizophrenia
late adolescence and early adulthood
Cannabis and Schizophrenia
increases risk 6x
what are the prognostic variables for Schizophrenia
- Positive symptoms: better
- Negative symptoms: poor
- Better prognosis: pts with mood disorders= schizoaffective, major Depression with psychotic features or bipolar
- Poor prognosis: Negative symptoms, poor cognitive performance on testing, poor supports, younger onset
- Poor premorbid functioning, insidious onset
what are the positive symptoms of schizophrenia
- symptoms added to presentation
- typically present in Active phase
- Delusions
- Hallucinations
- Catatonia
- Agitation
What are the negative symptoms of Schizophrenia?
- Symptoms that appear missing from the presentation
- Typically present in Residual phase
- Affective flattening
- Apathy
- Social Withdrawal
- Anhedonia (no fun)
- Poverty of thought
- Content of speech
for Schizophrenia, symptoms must be present for how long?
6 months
Schizophrenia higher rates in pts born in what months?
winter and early spring . . possible prenatal exposure to influenza virus
current hypothesis for schizophrenia
- increased dopamine in neuronal tracts: blocks pathways responsible for symptoms, Target of many anti-psychotic drugs
- Increased serotonin and norepinephrine
- Decreased GABA and Glutamate receptors
Brain imaging and schizophrenia
enlarged ventricles
are Schizophrenics more likely to commit homicide?
no
what would you give a violent schizophrenic in the ED?
Lorazepam and haloperidol IM
leading cause of death in Schizophrenics?
Suicide
what may reduce risk of suicide in schizophrenics?
Clozapine
