Psychosis Meds Flashcards
Haloperidol (Haldol) Chlorpromazine (Thorazine) Fluphenazine (Prolixin) Thiothixene (Navane) ACTION
Alters effects of dopamine in the CNS
Has anticholinergic & alpha adrenergic blocking activity
Haloperidol (Haldol)
Chlorpromazine (Thorazine)
Fluphenazine (Prolixin)
Thiothixene (Navane)
Conventional Antipsychotics
Haloperidol (Haldol) Chlorpromazine (Thorazine) Fluphenazine (Prolixin) Thiothixene (Navane) ADVERSE EFFECTS
Agranulocytosis Anticholinergic effects EPS NMS Ortho hypotension Seizures
Acute dystonia
Severe spasm of tongue, neck, face, and back
Crisis situation requiring treatment
Treat with anticholinergics
Parkinsonism
Bradykinesia, rigidity, shuffling gait, drooling, tremors
Treat with benztropine, diphenhydramine, or amantadine
Akathisia
Inability to sit or stand still
Beta blockers, benzodiazepines, anticholinergics
Tardive Dyskinesia
Late EPS
Involuntary movements of tongue, face, such as lip smacking
Involuntary movements of the arms, legs, and trunk
If TD appears, lower dose or switch to a new medication
Neuroleptic Malignant Syndrome
Sudden high fever BP fluctuations Dysrhythmias Muscle Rigidity*** pipe-like arms Changes in LOC Stop medication, occurs within 2 weeks of therapy
Risperidone (Risperidal)
ACTION
Blocks receptors for dopamine and serotonin in CNS
Risperidone (Risperidal) Ziprasidone (Geodon) Olanzapine (Zyprexa) Aripiprazole (Abilify) SIDE EFFECTS
DM Weight gain Ortho hypotension Anticholinergic effects Mild EPS, such as tremor
Adderall
Methylphenidate (Concerta, Ritalin)
CNS stimulant
Adderall
Methylphenidate (Concerta, Ritalin)
ACTION
Raise levels of NE, serotonin, and dopamine
Adderall
Methylphenidate (Concerta, Ritalin)
ADVERSE EFFECTS
Insomnia, restlessness
Weight loss
Cardiovascular effects (dysrhythmias, chest pain)
Withdrawal reaction can lead to depression
aripiprazole (Abilify)
ADVERSE EFFECTS
Lower risk for Risperidal's adverse effects Sedation Headache Anxiety Insomnia GI upset
Olanzapine (Zyprexa)
ADVERSE EFFECTS
Low risk of EPS High risk of diabetes, weight gain Sedation Anticholinergic effects Ortho hypotension