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Mental Health > Depression Meds > Flashcards

Depression Meds Flashcards

1
Q

TCAs

A

Amitriptyline (Elavil)

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2
Q

Amitriptyline (Elavil)

ACTION

A

Block reuptake of NE and serotonin in the synaptic space, thereby intensifying the effects of these neurotransmitters

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3
Q

Amitriptyline (Elavil)

ADVERSE EFFECTS

A

Orthostatic hypotension - slow position changes
Anticholinergic effects - sunglasses, hydrate
Sedation - take at bedtime
Toxicity
Decreased seizure threshold
Excessive sweating

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4
Q

Amitriptyline (Elavil)

TOXICITY S/S

A 
Dysrhythmias
Mental confusion
Agitation
Seizures
Coma
Possible death
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5
Q

Amitriptyline (Elavil)

INTERACTIONS

A

MAOIs
Antihistamines & other anticholinergic agents
Direct acting sympathomimetics
Alcohol, benzodiazepines, opioids, & antihistamines (CNS depressants)

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6
Q

SSRIs

A

Citalopram (Celexa)
Fluoxetine (Prozac)
Sertraline (Zoloft)

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7
Q

Citalopram (Celexa)
Fluoxetine (Prozac)
Sertraline (Zoloft)
ACTION

A

Block reuptake of serotonin in the synaptic space, thereby intensifying effects of serotonin

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8
Q

Citalopram (Celexa)
Fluoxetine (Prozac)
Sertraline (Zoloft)
ADVERSE EFFECTS

A 
Sexual dysfunction
CNS stimulation - take in morning, avoid caffeine
Weight loss followed by weight gain
Serotonin syndrome
Withdrawal syndrome - taper
Hyponatremia
Rash
Sleepiness, faintness, lightheadedness
GI bleeding
Bruxism
Take with food in morning
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9
Q

SEROTONIN SYNDROME S/S

A 
Mental confusion, difficulty concentrating
Abdominal pain
Diarrhea
Agitation
Fever
Anxiety
Hallucinations
Hyperreflexia, incoordination
Diaphoresis
Tremors
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10
Q

Citalopram (Celexa)
Fluoxetine (Prozac)
Sertraline (Zoloft)
INTERACTIONS

A

MAOIs, TCAs, St. John’s wort - d/c MAOI 14 days āc SSRI
Warfarin - increased warfarin levels in blood
NSAIDs & anticoagulants

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11
Q

MAOI

A

Phenelzine (Nardil)

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12
Q

Phenelzine (Nardil)

ACTION

A

Block MAO in the brain, thereby intensifying effects of NE, dopamine, and serotonin

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13
Q

Phenelzine (Nardil)

ADVERSE EFFECTS

A

CNS stimulation
Orthostatic hypotension
Hypertensive crisis

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14
Q

Hypertensive crisis s/s

A

Headache
Nausea
Increased HR
Increased BP

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15
Q

Phenelzine (Nardil)

INTERACTIONS

A 
Sympathomimetic medications
TCAs, SSRIs
Antihypertensives
meperidine (Demerol) - lead to hyperpyrexia
Vasopressors
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16
Q

Atypical Antidepressants

A

Bupropion (Wellbutrin)

17
Q

Bupropion (Wellbutrin)

ACTION

A

Inhibits dopamine uptake

18
Q

Bupropion (Wellbutrin)

ADVERSE EFFECTS

A

Anticholinergic symptoms
Suppression of appetite
Seizures

19
Q

Bupropion (Wellbutrin)

INTERACTIONS

A

MAOIs

20
Q

SNRIs

A

Venlafaxine (Effexor)

Duloxetine (Cymbalta)

21
Q

Venlafaxine (Effexor)
Duloxetine (Cymbalta)
ACTION

A

Inhibit reuptake of serotonin and NE thereby increasing amount available to the brain for impulse transmission

22
Q

Venlafaxine (Effexor)
Duloxetine (Cymbalta)
ADVERSE EFFECTS

A 
Headache
Nausea
Agitation, anxiety
Hyponatremia
Weight loss
Sexual dysfunction
Withdrawal - taper medication

Mental Health (17 decks)

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