Psycho pharma

Question 1

positive symptoms of schizophrenia is due to dopamine overactivity in the mesocortical pathway. True or false

Answer 1

False. positive symptoms of schizophrenia is due to dopamine overactivity in the mesolimbic pathway

Question 2

negative symptoms of schizophrenia is due to dopamine deficiency in the mesolimbic pathway. True or false

Answer 2

False. due to dopamine deficiency in the mesocortical pathway

Question 3

example of 3rd generation atypical antipsychotics

Answer 3

aripiprazole

Question 4

example of typical antipsychotics

Answer 4

haloperidol, chlorpromazine, thioridazine, thiothixene, trifluoperazine

Question 5

Aripiprazole is a 3rd generation atypical antipsychotic. it is a D2 receptor partial antagonist. True or false

Answer 5

false. D2 receptor partial agonist

Question 6

what major class of antipsychotics causes EPS

Answer 6

typical antipsychotics

Question 7

what anti epileptic drug has the widest spectrum of action meaning it can be used in various types of seizures

Answer 7

valproic acid

Question 8

Ethosuximide is the an anti epileptic drug that can only be used in this type of seizure

Answer 8

for absence seizure only

Question 9

this adverse effect of antipsychotic is characterized as choreoathetoid movement that is due to relative cholinergic deficiency due to supersensitivity of dopamine receptors in the caudate-putamen

Answer 9

tardive dyskinesia

Question 10

this adverse effect of antipsychotic manifests as marked rigidity, rapid rise in temperature, autonomic instability, and elevated muscle CK

Answer 10

neuroleptic malignant syndrome

Question 11

clomipramine, imipramine, amitriptyline, trimipramine are examples of what drug class

Answer 11

tricyclic antidepressents

Question 12

escitalopram, paroxetine, fluoxetine, sertraline are examples of what drug class

Answer 12

SSRI - selective serotonin reuptake inhibitor

Question 13

venlafaxine, duloxetine are examples of what drug class

Answer 13

SNRI (selective serotonin and noradrenaline reuptake inhibitor)

Question 14

raboxetine and atomoxetine are examples of what drug class

Answer 14

NARI (noradrenaline reuptake inhibitor

Question 15

example of noradrenaline and dopamine reuptake inhibitor (NDRI)

Answer 15

Bupropion

Question 16

mirtazapine belongs to what drug class

Answer 16

NaSSA - noradrenergic and specific serotonin antidepressant

Question 17

trazodone and nefazodone belong to what drug class

Answer 17

serotonin antagonist and reuptake inhibitor (SARI)

Question 18

common side effect of TCAs due to its alpha blocking ability

Answer 18

orthostatic hypotension

Question 19

useful for treatment of status epilepticus

Answer 19

diazepam

Question 20

useful in the treatment of myoclonic seizures, absence seizure, and infantile spasms

Answer 20

clonazepam

Question 21

DOC for bipolar disorder

Answer 21

atypical antipsychotics

Question 22

DOC for psychotic melancholia

Answer 22

TCAs

Question 23

DOC for non psychotic melancholia vs non-melancholic depression

Answer 23

For non psychotic melancholia, use SNRI. For non melancholic depression, use SSRI