Psycho pharma Flashcards
positive symptoms of schizophrenia is due to dopamine overactivity in the mesocortical pathway. True or false
False. positive symptoms of schizophrenia is due to dopamine overactivity in the mesolimbic pathway
negative symptoms of schizophrenia is due to dopamine deficiency in the mesolimbic pathway. True or false
False. due to dopamine deficiency in the mesocortical pathway
example of 3rd generation atypical antipsychotics
aripiprazole
example of typical antipsychotics
haloperidol, chlorpromazine, thioridazine, thiothixene, trifluoperazine
Aripiprazole is a 3rd generation atypical antipsychotic. it is a D2 receptor partial antagonist. True or false
false. D2 receptor partial agonist
what major class of antipsychotics causes EPS
typical antipsychotics
what anti epileptic drug has the widest spectrum of action meaning it can be used in various types of seizures
valproic acid
Ethosuximide is the an anti epileptic drug that can only be used in this type of seizure
for absence seizure only
this adverse effect of antipsychotic is characterized as choreoathetoid movement that is due to relative cholinergic deficiency due to supersensitivity of dopamine receptors in the caudate-putamen
tardive dyskinesia
this adverse effect of antipsychotic manifests as marked rigidity, rapid rise in temperature, autonomic instability, and elevated muscle CK
neuroleptic malignant syndrome
clomipramine, imipramine, amitriptyline, trimipramine are examples of what drug class
tricyclic antidepressents
escitalopram, paroxetine, fluoxetine, sertraline are examples of what drug class
SSRI - selective serotonin reuptake inhibitor
venlafaxine, duloxetine are examples of what drug class
SNRI (selective serotonin and noradrenaline reuptake inhibitor)
raboxetine and atomoxetine are examples of what drug class
NARI (noradrenaline reuptake inhibitor
example of noradrenaline and dopamine reuptake inhibitor (NDRI)
Bupropion
mirtazapine belongs to what drug class
NaSSA - noradrenergic and specific serotonin antidepressant
trazodone and nefazodone belong to what drug class
serotonin antagonist and reuptake inhibitor (SARI)
common side effect of TCAs due to its alpha blocking ability
orthostatic hypotension
useful for treatment of status epilepticus
diazepam
useful in the treatment of myoclonic seizures, absence seizure, and infantile spasms
clonazepam
DOC for bipolar disorder
atypical antipsychotics
DOC for psychotic melancholia
TCAs
DOC for non psychotic melancholia vs non-melancholic depression
For non psychotic melancholia, use SNRI. For non melancholic depression, use SSRI
