Anti TB, Anti Fungal, Anti Viral, Anti Malarial, Anti Protozoal

Question 1

Anti tb drug that inhibits mycolic acid

Answer 1

Isoniazid

Question 2

Anti tb drug that inhibits DNA dependent RNA polymerase

Answer 2

Rifampicin

Question 3

Anti tb drug that disrupts cell membrane metabolism and transport functions

Answer 3

Pyrazinamide

Question 4

Anti tb drug that inhibits arabinosyl transferase

Answer 4

Ethambutol

Question 5

Anti tb drug that inhibits protein synthesis by binding to 30s ribosomal unit

Answer 5

Streptomycin

Question 6

Which primary anti tb drug is most effective against rapidly growing extracellular (neutral ph) bacteria

Answer 6

Isoniazid

Question 7

Which primary anti tb drug is most effective against slowly growing extracellular (neutral ph) bacteria

Answer 7

Rifampicin

Question 8

Which primary anti tb drug is most effective against slowly growing intracellular (acidic ph) bacteria

Answer 8

Pyrazinamide

Question 9

Which primary anti tb drug has no effect on slowly growing extracellular (neutral ph) bacteria

Answer 9

Pyrazinamide and ethambutol

Question 10

Which primary anti tb drug has no effect on rapidly growing extracellular (neutral ph) bacteria

Answer 10

Pyrazinamide

Question 11

Resistance to this anti tb drug involves inhA, katG, aphc, and kasA genes

Answer 11

Isoniazid

Question 12

Resistance to this anti tb drug involves rpo B gene

Answer 12

Rifampicin

Question 13

Resistance to this anti tb drug involves pncA gene

Answer 13

Pyrazinamide

Question 14

Resistance to this anti tb drug involves emb B gene

Answer 14

Ethambutol

Question 15

Most potent sterilizing anti tb drug

Answer 15

Rifampicin

Question 16

Anti tb drug that causes peripheral neuropathy, seizures, hepatotoxicity, hemolysis in G6PD , drug induced lupus

Answer 16

Isoniazid

Question 17

Anti tb drug that causes discoloration of body fluids (red orange) , thromobcytopenia

Answer 17

Rifampicin

Question 18

Anti tb drug that causes hyperuri emia

Answer 18

Pyrazinamide

Question 19

Anti tb drug that causes retrobulbar neuritis, hyperuiricemia

Answer 19

Ethambutol

Question 20

DOC for non falciparum and sensitive falciparum malaria

Answer 20

Chloroquine

Question 21

anti malarial drug that can be used as treatment for rheumatic disease

Answer 21

chloroquine

Question 22

anti malarial drug with adverse effect of cinchonism charac by tinnitus, headache, dizziness, vomiting, flushing, visual disturbances

Answer 22

Quinine/quinidine

Question 23

anti malarial drug with AE of blackwater fever

Answer 23

quinine/quinidine

Question 24

anti malarial drug with AE of psychosis

Answer 24

mefloquine

Question 25

anti malarial drug that can be used for radical cure of p. vivax and p. ovale

Answer 25

primaquine

Question 26

most common AE of primaquine

Answer 26

hemolytic anemia or methemoglobinermia in G6PD deficiency

Question 27

DOC in the tx of all symptomatic amebiasi

Answer 27

Metronidazole

Question 28

DOC in the tx of giardiasis

Answer 28

Metronidazole

Question 29

DOC in the trichomoniasis

Answer 29

Metronidazole

Question 30

DOC in Clostridium difficile-induced pseudomembranous colitis

Answer 30

Metronidazole

Question 31

anti-helminth used for annual deworming of Filipino children 1 to 14 years of age

Answer 31

Albendazole

Question 32

DOC for hydatid cyst

Answer 32

Albendazole

Question 33

DOC for neurocysticercosis (in combination with steroids)

Answer 33

Albendazole

Question 34

DOC for cutaneous and visceral larva migrans

Answer 34

Albendazole

Question 35

DOC for intestinal capillariasis

Answer 35

Albendazole

Question 36

Anti-helminth that inhibit microtubule polymerization by binding to the parasite's beta tubulin, thus interfering with microtubule-dependent glucose uptake by the parasite leading to glycogen consumption and ATP depletion

Answer 36

Albendazole

Question 37

anti-helminth that depolarizes the NMJ of most intestinal nematodes resulting in their irreversible paralysis and allowing their natural expulsion

Answer 37

Pyrantel pamoate

Question 38

DOC for filariasis

Answer 38

DEC - diethylcarbamazine citrate

Question 39

DOC for loaiasis

Answer 39

DEC - diethylcarbamazine citrate

Question 40

Mazzoti reaction is AE of what drug

Answer 40

DEC - diethylcarbamazine citrate and Praziquantel

Question 41

anti-helminth that immobilizes microfilariae and alters their surface structure, displacing them from tissues and making them more susceptible to destruction by host defense mechanisms

Answer 41

DEC - diethylcarbamazine citrate

Question 42

anti-helminth that paralyzes the parasite by intesifying GABA-mediated transmission of signals in the parasite's peripheral nerves

Answer 42

Ivermectin

Question 43

DOC for onchocerciasis

Answer 43

Ivermectin

Question 44

DOC for strongyloidiasis

Answer 44

Ivermectin

Question 45

anti-helminth that increases the permeability of trematod and cestode cell membrane to calcium resulting to spastic paralysis and death

Answer 45

Praziquantel

Question 46

DOC for schistosomiasis

Answer 46

Praziquantel

Question 47

DOC for H. nana infection

Answer 47

Praziquantel

Question 48

Chemoprophylactic drug for malaria for areas without resistant P. falciparum

Answer 48

Chloroquine

Question 49

Chemoprophylactic drug for malaria for areas with chloroquine-resistant P. falciparum

Answer 49

Atovaquone-proguanil (Malarone) ORRRRRR Mefloquine

Question 50

Chemoprophylactic drug for malaria for areas with MDR P. falciparum

Answer 50

Doxycycline

Question 51

This antibiotic can be used for treatment of malaria. It is usually given together with quinine

Answer 51

Doxycycline

Question 52

DOC for asymptomatic intestinal amebic infections

Answer 52

Diloxanide furoate

Question 53

DOC for symptomatic amebic infection (regardless of severity)

Answer 53

Metronidazole + Diloxanide furoate

Question 54

DOC for early stage West VERSUS East African trypanosomiasis

Answer 54

West: Pentamidine East: Suramin

Question 55

Treatment for acute American trypanosomiasis (Chaga's disease)

Answer 55

Nifurtimox