Psychiatry Flashcards

1
Q

First line pharmacotherapy for depression

A

SSRIs

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2
Q

Antidepressants associated with hypertensive crisis

A

MAO-inhibitors

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3
Q

SE: galactorrhoea, impotence, menstrual dysfunction, decreased libido

A

Dopamine antagonists

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4
Q

A 17year old girl has left arm paralysis after her boyfriend dies in a car crash. No medical cause is found.

A

Conversion disorder

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5
Q

Name the defence mechanism: a mother who is angry at her husband yells at her child

A

Displacement

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6
Q

Name the defence mechanism: a girl who is upset with her best friend acts overly kind

A

Reaction formation

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7
Q

Name the defence mechanism: a man calmly describes a grisly murder

A

Isolation

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8
Q

Name the defence mechanism: a hospitalised 10 year old begins to wet his bed

A

Regression

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9
Q

Life threatening muscle rigidity; high fever; autonomic instability; confusion; elevated creatine phosphokinase

A

Neuroleptic malignant syndrome

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10
Q

Amenorrhoea, low body weight (<85%), bradycardia, abnormal body image in a young woman

A

Anorexia

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11
Q

A 35 year old man had recurrent episodes of palpitations, diaphoresis, and fear of impending doom

A

Panic disorder

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12
Q

The most serious side effect of clozapine

A

Agranulocytosis

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13
Q

21 year old man has 3 months of social withdrawal, worsening grades, flattened affect, and concrete thinking

A

Schizophreniform disorder

A diagnosis of schizophrenia requires >6 months of symptoms

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14
Q

Key side effects of atypical antipsychotics

A

Weight gain, T2DM, QT prolongation

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15
Q

A young weight lifter receives IV haloperidol and complains that his eyes are deviated sideways. Dx? Tx?

A

Acute dystonia (oculigyric crisis)

Tx: benztropine or diphenhydramine

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16
Q

Medication to avoid in patients with Hx alcohol withdrawal seizures

A

Neuroleptics (they can lower the seizure threshold)

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17
Q

A 13 year old boy has a history of theft, vandalism, and violence towards family pets

A

Conduct disorder.

Associated with antisocial personality disorder in adults

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18
Q

A 5 month old girl has reduced head growth, truncal discoordination, and decrease social interaction

A

Rett disorder

Loss of milestones is commonly described

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19
Q

A patient hasn’t slept for days, lost $20,000 gambling, is agitated and has pressured speech. Dx? Tx?

A

Acute mania

Tx: mood stabiliser e.g lithium

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20
Q

After a minor ‘fender bender’, a man wears a neck brace and request permanent disability

A

Malingering

21
Q

A nurse presents with severe hypoglycaemia; blood analysis reveals no elevation in C-peptide

A

Factitious disorder

22
Q

A patient spends most of his time acquiring cocaine despite losing his job and being threatened with legal charges

A

Substance use disorder

23
Q

Medication to avoid in patients with PTSD

A

Benzodiazepines (have a high addiction potential)

Patients commonly have a history of substance abuse

24
Q

A violent patient has vertical and horizontal nystagmus

A

Phencyclidine hydrochloride (PCP) intoxication

25
Q

A woman who was abused as a child frequently feels outside of or detached from her body

A

Depersonalisation disorder

26
Q

A schizophrenic patient takes haloperidol for 1 year and develops uncontrollable tongue movements. Dx? Tx?

A

Tardive dyskinesia

Tx: reduce /stop haloperidol

Change the antipsychotic e.g risperidone, clozapine

27
Q

A man with major depressive disorder is counselled to avoid tyramine-rich foods with his new medication. What class of drugs is he taking?

A

MAO- inhibitors

28
Q

Children must exhibit ADHD symptoms in …….

A

Two or more settings (e.g home and school)

29
Q

Which congenital conditions are associated with autism spectrum disorder?

A

Rett syndrome, tuberous sclerosis, & fragile X syndrome

30
Q

Conduct disorder - children or adults?

A

Children

31
Q

Antisocial personality disorder is seen in children or adults?

A

Adults

32
Q

Most common avoidable cause of intellectual disability in kids?

A

Fetal alcohol syndrome

33
Q

Coprolalia - definition and association

A

Repetition of obscene words (a kind of vocal tic)

Associated with Tourette syndrome

34
Q

Components of psychosis: delusions

A

Fixed false idiosyncratic belief

35
Q

Component of psychosis: hallucinations

A

Perception without an existing external stimulus

36
Q

Components of psychosis: illusion

A

Misperception of an actual external stimulus

37
Q

Duration and characteristics of brief psychotic disorder (psychotic disorder)

A

> 1 day and <1 month

NB: same presentation as schizophrenia, but are usually preceded by stressors, have no prior episodes, are less likely to have negative symptoms & have better lifetime prognosis

38
Q

Duration and characteristics of schizophreniform disorder (psychotic disorder)

A

1 month < < 6 months

NB: same presentation as schizophrenia but usually preceded by stressors, have no prior episodes, less likely to have negative symptoms, better lifetime prognosis

39
Q

Duration and characteristics of schizophrenia (psychotic disorder)

A

> 6 months

40
Q

Duration and characteristics of schizoaffective disorder (psychotic disorder)

A

Schizophrenia + major affective disorder (major depressive or bipolar affective disorder)

41
Q

Characteristics of schizotypal disorder (personality disorder)

A

Magical thinking

42
Q

Characteristic of schizoid disorder (personality’s disorder)

A

Loners

43
Q

Characteristic of delusional disorder

A

Persistent NON-BIZARRE fixed delusions without disorganised thought process, hallucinations or negative symptoms of schizophrenia

Day to day functioning mostly unaffected

44
Q

Subtypes of delusional disorder

A

Jealous, paranoid, somatic, erotomanic, grandiose

45
Q

Examples of high potency typical antipsychotics

A

Haloperidol, fluphenazine

46
Q

Examples of low potency typical antipsychotics

A

Thioridazine, chlorpromazine

47
Q

Indications for typical antipsychotics

A

Psychotic disorders, acute mania, acute agitation, Tourette syndrome

48
Q

Typical antipsychotics more effective in (positive/negative) symptoms of schizophrenia. Mechanism?

A

Positive

Primarily block D2 receptors

49
Q

What do you consider if compliance to typical antipsychotics is an issue?

A

Depot preparations