Psych Disorders Due To Medications

Question 1

What psychiatric manifestation can the antiepileptic drug phenytoin produce?

Answer 1

Cognitive impairment

Acute toxicity causes sedation and confusion

Question 2

What psychiatric manifestation can the antiepileptic drug phenobarbital (barbiturate) produce?

Answer 2

Cognitive impairment

Question 3

What psychiatric manifestation can the antiepileptic drug topirimate (3) produce?

Answer 3

1. Cognitive impairment
2. Depression
3. Psychosis

Question 4

Which 2 HIV drugs may cause psych symptoms?

Answer 4

Efavirenz - any psychiatric sx

Zidovudine - depression, mania

Question 5

Treatment Catatonia? (3)

Answer 5

• Treat underlying cause
• benzo
• ECT if life-threatening

Question 6

Name 10 medications that may cause psychiatric symptoms

Answer 6

• Antibiotics: metronidazole, sulphonamides (depression)
• arvs
• anti-epileptics
• anti hypertensives: propranolol, clonidine (depression)
• anti-neoplastics
• anti-tb drugs: isoniazid, ethiomide, ethambutol (psychosis)
• amphotericin B (psychosis)
• corticosteroids (lability, euphoria, anxiety, depression, psychosis, delirium)
• histamine R antagonists : cimetidine,ranitidine
• OCP (depression)