Psych Disorders Due To AMC Flashcards
Name 4 infections diseases that commonly manifest with neuropsychiatric manifestations
- Hiv/aids
- Syphilis
- Lyme disease
- Prion disease eg creutzfeldt - Jakob disease
Name. 4 rheumatological/ autoimmune conditions with neuropsychiatric manifestations
- SLE
- Sarcoidosis
- Vasculitides
- Multiple sclerosis
Name 4 endocrinological conditions with neuropsych manifestations
1 cushings
- hypo/ hyper thyroidism
- Hypo /hyper parathyroidism
- Adrenal insufficiency
Name 6 NB vitamin deficiencies conditions with neuropsych manifestations
Thiamine (B1) B12 B3 B6 Folate Vit D
Name an NB micronutrient abnormality with neuropsych manifestations
Hypo/hyper calcaemia
Name 5 diagnostic considerations if a patient has psychiatric symptoms and a medical condition?
1 delirium
- MC causing psych symptoms
- AMC and psych symptoms co-exist/co-morbid
- Psychological response to AMC
- Medication causing psychiatric symptoms
Name 3 red flags and 3 orange flags pointing to AMC as a cause of psych symptoms
Red flags: 1. late onset of initial presentation 2. Known MC or abnormal physical exam 3. Medication use (esp new ) Orange flags: atypical presentation, no family history, treatment resistance or unusual treatment response.
Name 5 situations in which brain imaging (preferably MRI) is mandatory
- Localising signs on neurological exam ( ID focal path and/or space - occupying lesion)
- New onset seizures
- Cognitive impairment excessive or atypical for psych condition
- Possible encephalitis (pyrexia, headache, seizures, cognitive impair)
- Possible fall, cognitive impair, vulnerability factors eg anticoag or alcoholism (exclude subdural haematoma )
Name 5 metabolic conditions with neuropsych manifestations
- Acute hepatic porphyrias
- Wilson’s disease! (Excess copper)
- Amyloidosis
- Hepatic encephalopathy
- uraemia
In What type of seizure is psychopathology commonly found?
Complex partial seizures (ie focal seizures in which patient has lost conciousness)
What is the most specific lab test for epilepsy?
Elevated prolactin 15-20 minutes after seizure
Which psychiatric drugs are contraindicated in epilepsy? (5)
- Tricyclic antidepressants
- bupropion (atypical antidepressant)
- Low potency typical antipsychotics (phenothiazines) eg chlorpromazine, thioridazine
- Clozapine: dibenzodiazepines atypical neuroleptic
- Lithium
What is the best class of antidepressant for an epilepsy patient?
SSRI
Do not give TCA or bupropion
What is the best antipsychotic to prescribe to epilepsy patient?
Haloperidol (low pro-convulsive effect)
Neuropsych symptoms are more common in tumours at which 2 locations in the brain?
Frontal and temporal