Pseudogout ☺️ Flashcards
1
Q
Risk factors
A
Older age, genetics
Joint trauma
Excess Ca, not enough Mg
Hypothyroidism, hyperPTH
2
Q
Presentation
A
Similar to septic arthritis
- rapid onset pain
- heat, pain, red, swelling
- larger joints, elbow, wrist, ankle
- joint effusion
3
Q
Investigations
Xray findings
Synovial fluid analysis
A
- FBC => leukocytosis
- high CRP, ESR
- U&E => assess for any kidney damage to rule out gout
Xray - Calcium pyrophosphate visible as chondrocalcinosis
DEFINITIVE - synovial fluid aspiration => positively birefringent rhomboid crystals under polarised light
4
Q
Pathophysiology
A
Inflammatory crystal monoarthropathy caused by deposition of calcium pyrophosphate crystals in the knee/wrist/larger joints shed from cartilage
5
Q
Management -aims to reduce pain and improve joint function
- acute
- definitive
- lifestyle changes
A
1st line - NSAIDs
- CS
- colchicine
Definitive - joint replacement
Lifestyle => cool packs, rest, aspiration
