Noradrenaline ☺️ Flashcards
1
Q
How is noradrenaline synthesised
A
Same pathway as dopamine from tyrosine
Dopamine =(dopamine b hydroxylase)=> Noradrenaline
2
Q
How is noradrenaline stored
A
VMAT
3
Q
How is noradrenaline released
A
Ca mediated exocytosis
4
Q
Which receptors respond to noradrenaline
A
a receptors
- a1 = SM, arterioles, Gq
- a2 = presynaptic membranes Gi
Adrenaline binds to both a and b receptors
5
Q
How is noradrenaline reuptaken
A
Noradrenaline reuptake channel
6
Q
How is noradrenaline degraded
A
MAO
COMT
7
Q
Where is noradrenaline released from
Where does it go to?
A
Locus coeruleus => all over the brain and a1, 2 receptors in body
