Proximal myopathy Flashcards

1
Q

What is the definition of proximal myopathy?

A

Symmetrical weakness of the upper part of the muscle

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2
Q

What are the risk factors/aetiology of proximal myopathy?

A
  • Hyperthyroidism
  • Hypothyroidism
  • Acromegaly
  • Cushings syndrome
  • Myasthenia gravis
  • Osteomalacia
  • Disorder of Ca metabolism
  • Hypo/hyperkalaemia
  • Idiopathic inflammatory myopathies
  • Neuropathies
  • Polymyalgia rheumatica
  • Hereditary myopathies
  • Renal disease
  • Malignancy
  • Infections
  • Sarcoidosis
  • Drugs e.g. steroids, statins
  • Alcohol
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3
Q

What are the signs/symptoms of proximal myopathy?

A
  • Unable to rise from a seated position without the use of their arms
  • Difficulty climbing stairs
  • Difficulty shaving
  • Difficulty combing hair
  • Malasia
  • Paraesthesia
  • Atrophy of muscles
  • Myalgia
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4
Q

What investigations are conducted in the case of proximal myopathy?

A
  • Creatinine kinase
  • FBC
  • ESR
  • U&Es
  • TFTs
  • Vit D levels
  • Antinuclear antibodies
  • ECG
  • Urinalysis
  • Electromyography
  • MRI
  • Muscle biopsy
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5
Q

What are the pharmacological treatments for proximal myopathy?

A
  • Removal of offending agent
  • Correcting endocrine/metabolic problem
  • Corticosteroids
  • Immunosuppressant
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6
Q

What are the non pharmacological treatments for proximal myopathy?

A
  • Genetic counselling

* Physical aids

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