Proteins B1.2 Flashcards

1
Q

What is the basic amino acid structure?

A

amine group (-NH2) on the left, carboxyl group (-COOH) on the right, both bonded to the alpha carbon in the middle. The alpha carbon is also bonded to a hydrogen and R-group on the top and bottom.

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2
Q

The amine group of an amino acid and what does it do?

A

can become protonated to form NH3+. is basic because of accepting protons

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3
Q

The carboxyl group of an amino acid and what does it do?

A

can donate protons and is acidic because of that.
joins with the amine group of another amino acid in condensation to form peptide bond.

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4
Q

Amino acids are the what of proteins?

A

monomers

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5
Q

Condensation of amino acids

A

-OH of carboxyl group combines with the -H of the amine group of another amino acid to form a C-N peptide bond and water.

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6
Q

Oligopeptide?

A

anything 3-20 amino acids in a chain. polypeptide is more than 20

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7
Q

Protein is a what?

A

combination of polypeptides

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8
Q

What are essential amino acids?

A

can’t be synthesized by the body and must be obtained through food.

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9
Q

What are non-essential amino acids?

A

can be made from other amino acids.

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10
Q

What are conditionally essential amino acids?

A

are usually not essential + can be synthesized but in times of illness and stress will be unable to make and need it.

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11
Q

How many of the amino acids is essential? Where do they come from?

A

9/20
animals and dairy products

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12
Q

Vegan diets and amino acids?

A

vegan diets require attention to ensure essential amino acids are consumed because plants often do not have the same amino acids needed in one go

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13
Q

How are amino acids made?

A

the amino acid sequence of each polypeptide is store in a coded form in the base sequence of a gene (DNA). Goes through transcription and translation to create the RNA to which tRNAs bring the amino acids to.

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14
Q

Transcription in protein synthesis

A

copying the DNA code into an mRNA molecule

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15
Q

Translation in protein synthesis

A

changing mRNA sequence (codons) into amino acids (tRNA brings)

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16
Q

Where is the ribosome (to which the synthesis happens) in the cell?

A

located freely in cytoplasm OR membrane bound and associated with the rough ER.

17
Q

What is the unique shape of every protein caused by?

A

the type of amino acid and the R-group. structure is determined by the base sequence

18
Q

What does R-groups say about the amino acid?

A

it’s polarity

19
Q

Haemoglobin

A

in red blood cells to transport oxygen

20
Q

Immunoglobin

A

antibodies that bind to antigens (foreign) bacteria or pathogens to defend against them

21
Q

Rhodopsin

A

absorbs photons of light and has light sensitive pigment to see in eyes.

22
Q

Collagen

A

structural component of teeth, bones, and tendons. rope like, abundant

23
Q

Keratin

A

found in hair has high tensile strength used as structural building block

24
Q

Digestive enzymes

A

break down macromolecules to their monomers

25
Q

Insulin

A

reduces glucose concentration in blood

26
Q

Denaturation of proteins by?

A

heat and pH change

27
Q

What type of interaction does the 3D structures of protein have with each polypeptide?

A

hydrogen bonds which are weak or interactions between the R groups.
- easily broken via heat or pH

28
Q

Denaturalization via heat

A

vibrations in molecule break the bonds that make the polypeptide chains unfold and change shape.

29
Q

Denaturalization via pH

A

changes in pH means changes in attraction between R groups of the polypeptide/protein. the attractions are important for the shape of the protein

30
Q

Albumen in egg white

A

added heat break hydrogen bonds in egg making it cross-linked between sulfur R groups since water is trapped inside structure make INSOLUBLE.

31
Q

Denaturation is?

A

permanent and forms insoluble precipitate