Prostate Flashcards

1
Q

Normal prostate volume

A

<30cc

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2
Q

What area is the prostate located?

A

retroperitoneum

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3
Q
The prostate is bordered:
\_\_\_\_\_\_\_\_ by the public bone
\_\_\_\_\_\_ by the rectum
\_\_\_\_\_\_ by the urinary bladder
\_\_\_\_\_\_\_ by the urogenital diaphragm
A

anteriorly
posteriorly
superiorly
inferiorly

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4
Q

What are teh three major vessels that provide arterial blood to the prostate?

A

internal pudendal
inferior vesical
middle rectal arteries

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5
Q

apex

A

inferior portion of the gland situated superior to the urogenital diaphragm

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6
Q

base

A

superior portion of the gland situated below the inferior margin of the urinary bladder

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7
Q

seminal vesicles

A

two sac-like outpouchings of the vas deferens
situated adjacent to the sup/post aspect of the prostate,
b/w the urinary bladder and rectum
located post/inf to the bladder

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8
Q

ejaculatory ducts

A

duct that passes through the central zone and empties into the urethra
originates from the combination of the vas deferens and the seminal vesicle

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9
Q

verumontanum

A

longitudinal ridge within the urethra in which the orifices of the ejaculatory ducts are located on either side

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10
Q

corpora amylacea

A

calcifications commonly seen in the inner gland of the prostate

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11
Q

surgical capsule

A

demarcation between the inner gland (central and transitional zone) and the outer gland (peripheral zone)

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12
Q

eiffel tower sign

A

shadowing created by edge artifact or calcification of the prostatic urethra

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13
Q

The original concept of a 5 lobed prostate has been replaced the McNeal’s concept of zonal architecture, what are the glandular zones?

A

peripheral
central
transitional
fibromuscluar stroma

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14
Q

Peripheral zone

A

posteriorly/lat located portion of the prostate
extends into the apex of the prostate
containing 70% of the prostatic tissue, thus teh location of most prostate ca

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15
Q

Central Zone

A

superiorly located
contains 25% of tissue
ejaculatory ducts pass through from the seminal vesicles to the urethra

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16
Q

Transitional zone

A

5% of the tissue

origin of benign prostatic hyperplasia

17
Q

Fibrosmuscular Stroma

A

anteriorly located

non-glandular portion of prostate, hence not affected by prostate ca or hyperplasia

18
Q

classification or grading of prostate ca is established from the ____ ____ system.

A

Gleason Grading system
based on microscopic appearance, predominant pattern and second most common pattern are given a grade between 1-5 and the score is the sum
higehr the score the more aggressive

19
Q

In TRUS the image is inverted so that the rectum is displayed at the ______ of the screen.

A

bottom

20
Q

The incidence of prostate ca increases with the incidence of

A

age
family hx
race (at least 60% more common and 2-3 x more deadly among black men; If father or brother had it, then 2x risk, especially if brother
-lifetime risk is about 15% (1 in 6..67)

21
Q

Prostate specific antigen is a single-chain glycoprotein, what are the limits?

A

<4ng/mL = NML
4-10 = poetntially malig
>10 = most liekly ca
*PSA Velcoity - levels normally go up with age but they go up faster with ca
*PSA density - level/vol = higher indicates greater risk of ca

22
Q

PSA may be elevated from

A

infection, treated with antibiotics 4-6wks

23
Q

Classic appearance of prostate ca

A

varied
can be focal or diffuse
usually hypoechoic and peripherally orientated lesion
-can also appear hyperechoic or isoechoic
-not all hypo are cancerous
so….
the larger the lesion and the higher the PSA,more likely that a hypo lesion is ca

24
Q

Pre exam prep for TRUS

A

cleansing enema

pre and post prophylactic antibiotics

25
Q

Methods of prostate Bx

A

Lesion directed Bx- infreq used due to porr detection rate
Systematic Sextant Bx- 3 on RT and LT
Parasagittal Sextant Bx-including additional cores, 10, in eth lateral aspects of the peripheral zone

26
Q

Prostate staging 1-4

A

1-clinically nonpalpable
2-palpable nodule within prostate
3-palp extending through capsule
4-METs

27
Q

BPH

A

enlargement of the transitional zone of the prostate

28
Q

Symptoms of BPH

A

diffiuclt urination or voiding
urinary frequency
small stream

29
Q

Prostate anomalies

A
seminal vesicle agenesis
seminal vesicle cysts
utricle cysts
mulelrian duct cysts
ejaculatory duct cysts
30
Q

seminal vesicle agenesis

A

assoc with ipsilateral renal agenesis

31
Q

seminal vesicle cysts

A
  • post to bladder, arising from the seminal vesicles cephalic to the prostate
  • unilateral seminal vesicle cyst result from cong atresia of ejaculatory duct and are often assoc with ipsilateral renal agensis
  • seminal vesicle and wolfian duct cysts are lcoated off ML
  • Bilateral seminal cysts assoc with ADPKD
32
Q

Utricle cysts

A

-remnant of mulelrian duct in males which often presents as a sac with a slit like orifice at the apex of the verumontanum that prjects upward and backward int the substance of teh prostate
-tear drop shape at ML
assoc with hypospadies, crytorchidism, unilateral renal agenesis

33
Q

mulelrian duct cysts

A

remnant of the caudal ends of the fused mulelrian duct, typically regresses in utero
ML, post to bLD
-do not communicate with the prostatic urethra

34
Q

ejaculatory duct cysts

A
  • lateral and occur due to obstruction, cong or acq

- resulting in hematospermia, ejaculatory pain and infertility