Primary bone tumors

Question 1

Benign tumor: x2

Answer 1

Giant cell tumor (osteoclastoma)

Osteochondroma (exostosis)

Question 2

Benign:

giant cell tumor

Answer 2

Epi: 20-40 yrs of age
Epiphyseal end of long bone

Distal femur, proximal tibial = double bouble appearance

Question 3

Benign:

oesteochondroma

Answer 3

Most common benign, male <25 yrs

Mature bone with cartilagenous cap
Commonly origininate from long metaphysis
Malignant transformation to chondrosarcoma is RARE

Question 4

Malignant x3

Answer 4

Osteosarcoma
Ewings
Chondrosarcoma

Question 5

Malignant:

osteosarcoma

Answer 5

2nd most malignant (after MM)
Male> female 10-20 yrs
Risk factor: paget’s, bone infar, radiation, fam retinoblastoma

Metaphysis of lone bone, arounnddistal femur, proximal tibial

Codman’s angle (elevation of periosteum) or sunburst

Question 6

Malignant:

Ewing’s sarcoma

Answer 6

Boy < 15 yrs age
Diaphysis of long bone, pelvis, scapula, ribs

Anaplastic small blue cells
Extremely aggressive with early mets

Onion skin appearance

11,22 translocation

Question 7

Malignant:

Chondrosarcoma

Answer 7

Men 30-60 yrs of age
Usually in pelvis, spine, scapula, humerus, tibia or femur

Malignant cartilagnous tumor
Either 1’ origin or from osteochondroma

Expansile glistening mass within the medullary cavity