Lab values in bone disorders

Question 1

Osteoporosis

Answer 1

Serum Ca: none
Phosphate: none
ALP: none
PTH:none

Decreased bone mass

Question 2

Osteopetrosis

Answer 2

Serum Ca: low
Phosphate: normal
ALP: elevated
PTH: normal

Thickened dense bone

Question 3

Osteomalacia/rickets

Answer 3

Serum Ca: low
Phosphate: low
ALP: high
PTH: high

Soft bone

Question 4

Osteitis fibrosa cystica

Answer 4

Serum Ca: high
Phosphate: low
ALP: high
PTH: high

Brown tumors of hyperPTH

Question 5

Paget’s disease of bone

Answer 5

Serum Ca: normal
Phosphate: normal
ALP: high
PTH: normal

abnormal bone architecture