Polymyositis/dermatomyositis Flashcards

1
Q

Polymyositis

A

Progressive symmetric proximal weakness
Endomysial inflam with CD8+

Most often shoulders

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2
Q

Dermatomyositis

A
Similar to polymyositis
Also involves malar rash ( similar to SLE)
Helitrope rash
Shawl and face rash, 
Mechanics hand

Increased risk of occult malignancy
Perimysial inflam and atrophy with CD4+ T cells

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3
Q

Finding in both

A

Elevated CK
Positive ANA
Positive anti-Jo 1

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