Polymyositis/dermatomyositis Flashcards
1
Q
Polymyositis
A
Progressive symmetric proximal weakness
Endomysial inflam with CD8+
Most often shoulders
2
Q
Dermatomyositis
A
Similar to polymyositis Also involves malar rash ( similar to SLE) Helitrope rash Shawl and face rash, Mechanics hand
Increased risk of occult malignancy
Perimysial inflam and atrophy with CD4+ T cells
3
Q
Finding in both
A
Elevated CK
Positive ANA
Positive anti-Jo 1