Osteoarthritis vs. RA Flashcards
1
Q
Etiology
A
OS: mechanical
RA: autoimmune, Type III
2
Q
Joint finding
A
OS: osteophyte, ivory-bone, DIP (Hebereden) and PIP (Bouchard), no MCP
RA: pannus in MCP/PIP, no DIP, subQ RA nodule (fibrinoid necrosis) ulnar deviation of fingers. subluxation, Baker’s cyst
3
Q
Predisposing factors
A
OS: age, obesity, joint deformity
RA: Female > male, 80% with RA (anti IgG), anti cyclic citrullinate peptide Ab, HLA-DR4
4
Q
Presentation
A
OS: pain in weight bearing point, improve with rest, bow legged
RA: morning stiffness, improve with use, systemic symptoms (fever, fatigue, pleuritis, pericarditis)
5
Q
Treatment
A
OS: NSAIDs, intra-articular glucocorticoid
RA: NSAIDs, glucocorticoid, disease modifying agents (MTX, sulfasalazine, TNF inhibitors)
