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STEP1: MSK > Bilstering disorders > Flashcards

Bilstering disorders Flashcards

1
Q

Pemphigus vulgaris

A

IgG against desmoglein
Involves skin and oral mucosa

IF: around epidermal

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2
Q

Bullous pemphigoid

A

IgG against hemidesmosomes
IF: linear

Eosinophils within tense blisters
Spares oral mucosal (vs. vulgaris)

Negative Nikolsky’s skin

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3
Q

Dermatitis herpetiform

A

Pruritic papules, vesicles, bullae
Deposits of IgA at dermal papillae
Associated with celiac

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4
Q

Erythema multiforme

A

Infection (Mycoplasma, HSV)
Drug (sulfa, beta lactame, phenytoin)
Cancer
Autoimmune

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5
Q

Stevens Jonhnson

A

Fever, bullae, necrosis

Typically 2 mucus membranes involved
If more than 30% of body surface, toxic epidermal necrolysis.

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STEP1: MSK (31 decks)

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