Prenatal Development & Birth Flashcards
Heredity
the transmission of genetic material from one generation to another
Epigenetics
heritable variations in gene expression that do not involve DNA sequence changes
Mutation
a sudden or accidental variation in a heritable characteristic that affects the composition of genes
Monozygotic (MZ) Twins
twins that derive from a single zygote that was split in two, identical twins
Dizygotic Twins (DZ) Twins
twins that derive from two separate zygotes, fraternal twins
Down Syndrome
a chromosomal abnormality characterized by intellectual challenges and caused by an extra chromosome on the 21st pair
Phenylketonuria (PKU)
a genetic abnormality in which phenylalanine builds up and causes intellectual challenges
Huntington Disease
a fatal genetic neurological disorder whose onset takes place in middle age, it is a dominant trait
Sickle-cell Anemia
a genetic disorder that decreases the blood’s capacity to carry oxygen
Tay-Sachs Disease
a fatal genetic neurological disorder that causes degeneration and premature birth
Cystic Fibrosis
a fatal genetic disorder in which mucus obstructs the lungs and pancreas
Hemophilia
a genetic disorder in which blood does not clot properly
Muscular Dystrophy
a chronic disease characterized by a progressive wasting away of the muscles
Color Blindness
a sex-linked condition that makes it difficult to differentiate various colors
Amniocentesis
a procedure for drawing and examining fetal cells sloughed off into amniotic fluid to determine the prescence of various disorders
Chronic Villus Sampling (CVS)
a method for prenatal detection of genetic abnormalities that samples the membrane enveloping the amniotic sac and fetus
Alpha-Fetoprotein (AFP)
a blood test that assesses the mothers blood level of the alpha-fetoprotein, a substance that is linked to the fetal neural tube defects
Reaction Range
the interaction between nature and nurture
What does infertility look like in women?
irregular (or lack of) ovulation
pelvic inflammatory
endometriosis
What does infertility look like in men?
low sperm count or lack of sperm
low sperm motility
What is assisted human reproduction?
fertility drugs
in vitro fertilization: fertilization occurs outside, zygote then implanted
artificial insemination: direct sperm injection into uterus
What are the characteristics of the first trimester of pregnancy?
first 12 weeks, dating ultrasound, morning sickness, 15% of pregnancies end in miscarriage
What are the characteristics of the second trimester of pregnancy?
from the 13th to the 24th week, anatomic ultrasound to check if baby is developing correctly, gestational diabetes, begin to feel fetus movement
What are the characteristics of the third trimester of pregnancy?
from the 25th week, toxemia: sudden increase in blood pressure that could lead to a stroke
What are the stages of prenatal development?
germinal
embryonic
fetal
What is the germinal stage?
first two weeks
from conception to implantation
zygote –> blastocyst
cell specialization: placenta, umbilical cord, embryo
What is the embryonic stage?
after implantation to the end of week 8
placenta develops and takes charge of hormone production
Y chromosome signals for androgen secretion
organogenesis: foundational structures of organ systems (blastocyst)
What is the fetal stage?
beginning of week 9 to the end of gestation
fetus growth
refinements of organ system: become more specialized
13th to 21st week: neuronal proliferation, respond to soundwaves
viability: end the 22nd week is the earliest a baby can be born and survive outside the uterus
32nd to 33rd week: fetus can distinguish between novel and familiar stimuli
What is the ectoderm?
nervous system, sensory organs, nails, hair, teeth, outer layer of skin
What is the endoderm?
digestive and respiratory system, liver, pancreas
What is the mesoderm?
excretory, reproductory, and circulatory systems, skeleton, muscles, inner layer of skin
What are some autosomal disorders caused by recessive genes?
phenylketonuria (PKU)
sickle-cell disease
Tay-Sachs disease
cystic fibrosis
What are some autosomal disorders caused by dominant genes?
Huntington’s disease
What are some sex-linked disorders caused by abnormalities on the X chromosome?
Red-green color blindness
Hemophilia: blood doesn’t clot normally
Fragile-X chromosome: cognitive and behavioral impairments
Duchenne muscular dystrophy
What are some examples of trisomy disorders?
trisomy 21: down syndrome
trisomy 13 and 18: fatal, won’t survive first year
What is Klinefelter’s syndrome?
XXY
tall stature, poor beard growth, minor breast development, female pubic hair pattern, testicular atrophy
What is Turner’s syndrome?
XO
short stature, webbed neck, shield chest, underdeveloped breasts and widely spread nipples, rudimentary ovaries, nevi
How do viral infections affect prenatal development?
rubella: blindness, deafness, heart defects, or brain damage
zika virus: microcephaly, neurological deficits
cytomegalovirus: deafness, CNS damage, intellectual delay
HIV: weakens immune system
How do prescription and over-the-counter drugs affect prenatal development?
Thalidomide in the 60s caused a lot of babies were born missing limbs
How does tobacco affect prenatal development?
miscarriage, stillborn, premature birth, low-birth weight, neurobehavioral disorders
How does alcohol affect prenatal development?
FASD, learning and behavioral difficulties, mental health problems
How does cannabis affect prenatal development?
potential neurobiological and neurocognitive risks
How do illicit drugs affect prenatal development?
premature birth, miscarriage, early death, withdrawal symptoms