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BIOCHEMISTRY - 1st Year 1st Sem Comprehensive Exam > PREFI - VITAMINS, LIPID TRANSPORT, RBC/WBC, CHOL METABOLISM (2022) > Flashcards

PREFI - VITAMINS, LIPID TRANSPORT, RBC/WBC, CHOL METABOLISM (2022) Flashcards

1
Q

Pruritis and Headache is a symptom of?

A

Hypervitaminosis

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2
Q

All of the ff are symptoms of Hypervitaminosis EXCEPT;

A

Splenomegaly

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3
Q

Riboflavin is used in these pathways EXCEPT

A

Glycolysis

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4
Q

Dihydrofolate reductase inhibitor

A

Trimethoprim

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5
Q

Dietary Folic acid requirement

A

0.4 mg

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6
Q

Deficiency of biotin

A

Ingestion of avidin

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7
Q

Plant source of vitamin D

A

Ergocalciferol

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8
Q

Night blindness

A

Destroyed visual

cells

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9
Q

Dry, keratinization and blindness of conjunctiva

A

Xeropthalmia

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10
Q

Dry skin and progressive paralysis

A

Vitamin B1

Thiamine

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11
Q

Vegetarian will become deficient of

A

Vitamin B12

Cobalamin

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12
Q

Site of synthesis of retinol

A

Retina

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13
Q

Coenzyme of Amino acid metabolism in transamination and

decarboxylation

A

Pyridoxal PO4

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14
Q

Which of the ff is not a characteristic of scurvy?

A

Demineralization

of bone

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15
Q

What causes Folate trap?

A

Vitamin B12

deficiency

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16
Q

What prevents oxidation of PUFA(PolyunsaturatedFattyacid)

A

Vitamin E

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17
Q

Lactic acidosis is seen in deficiency of?

A

Vitamin B1

thiamine

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18
Q

Carcinoid is associated with

A

Niacin

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19
Q

Activate glutamate residue to form carboxyglutamate

A

Vitamin K

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20
Q

Hemolytic Anemia in premature infants

A

Vitamin E

deficiency

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21
Q

Adult w/ Vitamin A deficiency, should take

A

More than 1000

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22
Q

Prolonged use of antibiotic will lead to

A

Vitamin K

deficiency

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23
Q

Antibiotic that causes Vitamin K deficiency

A

Cephalosporin

24
Q

Primary function, as antioxidant in prevention of non-enzymatic
oxidation of cell components and free radicals

A

Vitamin E

25
Q

Cofactor of A-ketoglutarate dehydrogenase

A

Thiamine

pyrophosphate

26
Q

The 1st cell that responds on inflammation

A

Neutrophils

27
Q

Which of the ff does not belong to the group?

A

Lymphocyte
*PS Lymphocyte
and Monocyte =
AGRANULOCYTE

28
Q

All cell lines comes from what cell line

A

Hemoblast

29
Q

Vitamin K deficiency will lead to the decrease in production of
what factor?

A

Prothrombin

30
Q

Erythroblastosis fetalis in common in

A 
Mother Rh (-)
Baby Rh (+)
31
Q

Type AB contains _____ antigen and ______ antibodies

A

AB and Neither

Anti-A and Anti-B

32
Q

The conversion of Heme to biliverdin

A

Heme oxygenase

33
Q

Which of the ff is NOT true?

A

Biliverdin is

reabsorb back toBM

34
Q 
ABO antibodies
are produced even
before antigen
exposure (Natural
occurring
antibodies) TRUE OR FALSE
A

TRUE

35
Q

Allergic and Parasitic Infection cell involve is?

A

Eosinophil

36
Q

Most abundant lipid in plasma

A

Cholesteryl ester

37
Q

Most active plasma lipid

A

Unesterified FA

38
Q

Responsible for transport of all dietary lipids in circulation

A

Chylomicron

39
Q

Predominant lipoporotein in LDL

A

Cholesterol

40
Q

Final stage in the catabolism of VLDL

A

LDL (Low density

lipoprotein)

41
Q

Predominant lipoprotein in Chylomicrons

A

TAG

42
Q

Apolipoprotein found in HDL

A

Apo A

43
Q

Inhibitor of Lipoprotein lipase

A

Apo C III

44
Q

Cofactor for LCAT (Lecithin:Cholesterol acyltransferase)

A

Apo A1

45
Q

LDL
predominantly has
Cholesterol / TRUE OR FALSE

A

TRUE

46
Q

Reverse transport

A

HDL

47
Q

HDL major
component is bile
acids. TRUE OR FALSE

A

FALLS

48
Q

Increase triglyceride synthesis and VLDL secretion

A

Ethanol

49
Q

Competes with reducing equivalent from other substrates for

respiratory chain

A

NADH

50
Q

Parent steroid compound of cholesterol

A

Lanosterol

51
Q

Cholesterol ester storage disease

A

Wolman’s disease

52
Q

Source of carbons in cholesteroL

A

Acetyl CoA

53
Q

First and principal regulatory step in biosynthesis of Bile

A

Production of 7ahydroxylation
of
cholesterol

54
Q

Which of the ff. is not a product of Bile hydrolysis

A

Calcitriol

55
Q

Most abundant bile acid

A

Cholic acid

56
Q

Modification of bile making alkaline bile to produce bile salts

A

Conjugation with
glycine and
taurine residues

BIOCHEMISTRY - 1st Year 1st Sem Comprehensive Exam (16 decks)

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