MIDTERMS 1ST EVALS (2022)

Question 1

O-linked protein glycosylation except

Answer 1

GlcNac (it’s an N-linked)

Question 2

Lack of hepatic fructokinase causes
A-hereditary fructose intolerance
B-essential fructosuria
C-diabetic cataract
D-essential pentosuria

Answer 2

B-essential fructosuria

Question 3

Passive and active transport resemble at all points except:

Answer:

Answer 3

NO binding site for solute

Question 4

Cleavage of F16BP to Dihydroxyacteone and G3Phosphate –

Answer 4

ALDOLASE

Question 5

Occurs attack at night

Answer 5

PNH

Question 6

N-linked glycosidase, Mannose removal is catalyzed by :

Answer 6

Golgi Mannosidase II

Question 7

Glycolysis erythrocyte ending lactate

Answer 7

TRUE

Question 8

Enolase inhibited by

Answer 8

FLUORIDE

Question 9

Selectins

Answer 9

integrins pcam cd 31

Question 10

Pingpong mechanism

Answer 10

Facilitated Diffusion by TRANSPORTERS

Question 11

Where does PPP occur

Answer 11

CYTOSOL

Question 12

Enzymatic marker at ER

a. adenylyl cyclase
b. sialyl transferase
d. G6P

Answer 12

d. G6P

Question 13

DNA Transfection is dependent on

Answer 13

ENDOCYTOSIS

Question 14

Not true about ion channels

Answer 14

certain drugs do not inhibit

Question 15

Transketolase:

Answer 15

2 carbon

Question 16

N-linked addition of fucosyl, sialycyl happens in

Answer 16

Trans golgi

Question 17

What confers the negative charge of mucin

Answer 17

NeuAc and Sulfate

Question 18

A lack of hepatic fructokinase

Answer 18

essential FRUCTOSURIA

Question 19

This is the enzymatic marker of the trans golgi network

Answer 19

SIALYL TRANSFERASES

Question 20

Na-K pump 3 sodium out

Answer 20

Phosphorylation

Question 21

Na-K pump 2 potassium in

Answer 21

Dephosphorylation

Question 22

Mutation affecting a golgi located GDP-fucose transporter; psychomotor and
mental retardation:

Answer 22

Leukocyte Adhesion Def. Type II

Question 23

Mass spectrometry

Answer 23

info on molecular mass, composition, sequence and

branching of a glycan chain

Question 24

attachment of unsaturated fatty acid:

Answer 24

carbon 2

Question 25

bound to asparagine

Answer 25

Man3GlcNac2

Question 26

glucocorticoids

Answer 26

promotes gluconeogenesis

Question 27

defects in the synthesis of glycans in the protein alpha-dystroglycan and interacts
with laminin-2 in the basal lamina

Answer 27

Congenital Muscular Dystrophies

Question 28

source of glucuronate for incorporation into proteoglycan

Answer 28

UDP-glucuronate

Question 29

catalyzes of glucose to ascorbic acid

Answer 29

Glucoronate

Question 30

Common sugar of N-linked and O-linked:

Answer 30

N-acetylneuraminic acid

Question 31

True of fructose metabolism

Answer 31

bypass phosphofructokinase

Question 32

glucose to 6 phospogluconolactone

Answer 32

glucose 6 phosphate dehydrogenase

Question 33

High mannose glycoprotein may stop at this reaction

Answer 33

REACTION 3

Question 34

congetinal disorders if glycolysation

Answer 34

psychomotor retardation

Question 35

True of phosphoenolpyruvate carboxyknase

Answer 35

Phosphate donor is the product of succinate thiokinase in the TCA cycle

Question 36

Alcoholics are thiamin deficient

Answer 36

POOR DIET

Question 37

Responsible for minimizing hydrophilic character of peptide bond:

Answer 37

Alpha helical

structure of protein

Question 38

In humans, uronic acid pathway

Answer 38

D-gluronic to L-ascorbic

*not sure tho