MIDTERMS 1ST EVALS (2022) Flashcards
O-linked protein glycosylation except
GlcNac (it’s an N-linked)
Lack of hepatic fructokinase causes A-hereditary fructose intolerance B-essential fructosuria C-diabetic cataract D-essential pentosuria
B-essential fructosuria
Passive and active transport resemble at all points except:
Answer:
NO binding site for solute
Cleavage of F16BP to Dihydroxyacteone and G3Phosphate –
ALDOLASE
Occurs attack at night
PNH
N-linked glycosidase, Mannose removal is catalyzed by :
Golgi Mannosidase II
Glycolysis erythrocyte ending lactate
TRUE
Enolase inhibited by
FLUORIDE
Selectins
integrins pcam cd 31
Pingpong mechanism
Facilitated Diffusion by TRANSPORTERS
Where does PPP occur
CYTOSOL
Enzymatic marker at ER
a. adenylyl cyclase
b. sialyl transferase
d. G6P
d. G6P
DNA Transfection is dependent on
ENDOCYTOSIS
Not true about ion channels
certain drugs do not inhibit
Transketolase:
2 carbon
N-linked addition of fucosyl, sialycyl happens in
Trans golgi
What confers the negative charge of mucin
NeuAc and Sulfate
A lack of hepatic fructokinase
essential FRUCTOSURIA
This is the enzymatic marker of the trans golgi network
SIALYL TRANSFERASES
Na-K pump 3 sodium out
Phosphorylation
Na-K pump 2 potassium in
Dephosphorylation
Mutation affecting a golgi located GDP-fucose transporter; psychomotor and
mental retardation:
Leukocyte Adhesion Def. Type II
Mass spectrometry
info on molecular mass, composition, sequence and
branching of a glycan chain
attachment of unsaturated fatty acid:
carbon 2
bound to asparagine
Man3GlcNac2
glucocorticoids
promotes gluconeogenesis
defects in the synthesis of glycans in the protein alpha-dystroglycan and interacts
with laminin-2 in the basal lamina
Congenital Muscular Dystrophies
source of glucuronate for incorporation into proteoglycan
UDP-glucuronate
catalyzes of glucose to ascorbic acid
Glucoronate
Common sugar of N-linked and O-linked:
N-acetylneuraminic acid
True of fructose metabolism
bypass phosphofructokinase
glucose to 6 phospogluconolactone
glucose 6 phosphate dehydrogenase
High mannose glycoprotein may stop at this reaction
REACTION 3
congetinal disorders if glycolysation
psychomotor retardation
True of phosphoenolpyruvate carboxyknase
Phosphate donor is the product of succinate thiokinase in the TCA cycle
Alcoholics are thiamin deficient
POOR DIET
Responsible for minimizing hydrophilic character of peptide bond:
Alpha helical
structure of protein
In humans, uronic acid pathway
D-gluronic to L-ascorbic
*not sure tho
